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Understanding MLH1 and HNPCC: Hereditary Non-Polyposis Colon Cancer

This document provides a comprehensive overview of MLH1 and its critical role in Hereditary Non-Polyposis Colon Cancer (HNPCC), a genetic condition that increases the risk of colorectal cancer and other types of cancer. It discusses the genetic basis of the disease, its implications for cancer predisposition, the mechanisms behind DNA mismatch repair, and the importance of early diagnosis and management strategies. Understanding HNPCC is essential for individuals and families at risk to take preventative measures and undergo appropriate genetic testing.

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Understanding MLH1 and HNPCC: Hereditary Non-Polyposis Colon Cancer

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  12. vti_cachedlinkinfo:VX|H|http://www.healthsystem.virginia.edu/uvahealth/hub_cancer/hnpcc.cfm H|http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi H|http://www.virtuallaboratory.net/Biofundamentals/lectureNotes/AllGraphics/slippage.jpg H|http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi H|http://search.cancer.org/search H|http://www.ohsu.edu/tech-transfer/technologies/wct_389.shtml H|http://www.pdg.cnb.uam.es/UniPub/iHOP/gs/122799.html H|http://saturn.roswellpark.org/cmb/huberman/DNA_Repair/mmr.html H|http://www.ohsu.edu/tech-transfer/technologies/wct_389.shtml H|http://www.md.ucl.ac.be/entites/mint/intr/hainaut/dossierprojet/dossierdocsem/canccolrectgen/canccolrectgen.html H|http://www.virtuallaboratory.net/Biofundamentals/lectureNotes/AllGraphics/slippage.jpg H|http://www.exactsciences.com/pregen26/professionals/about_hnpcc/_index.htm H|http://www.healthsystem.virginia.edu/uvahealth/hub_cancer/hnpcc.cfm H|http://www.ohsu.edu/tech-transfer/technologies/wct_389.shtm H|http://www.kimmelcancercenter.org/kcc/HereditaryCancer/HNPCC/hnpcc.htm H|http://www.clevelandclinic.org/registries/inherited/hnpcc.htm H|http://ghr.nlm.nih.gov/gene=mlh1 H|http://www.ncbi.nlm.nih.gov/entrez/query.fcgi H|http://www.mdc-berlin.de/~gfactor/maus.jpg H|http://www.bio.unc.edu/courses/2005Spring/Biol169/ H|http://my.webmd.com/hw/colorectal_cancer/nord953.asp

  13. vti_cachedsvcrellinks:VX|NHHS|http://www.healthsystem.virginia.edu/uvahealth/hub_cancer/hnpcc.cfm NHHS|http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi NHHS|http://www.virtuallaboratory.net/Biofundamentals/lectureNotes/AllGraphics/slippage.jpg NHHS|http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi NHHS|http://search.cancer.org/search NHHS|http://www.ohsu.edu/tech-transfer/technologies/wct_389.shtml NHHS|http://www.pdg.cnb.uam.es/UniPub/iHOP/gs/122799.html NHHS|http://saturn.roswellpark.org/cmb/huberman/DNA_Repair/mmr.html NHHS|http://www.ohsu.edu/tech-transfer/technologies/wct_389.shtml NHHS|http://www.md.ucl.ac.be/entites/mint/intr/hainaut/dossierprojet/dossierdocsem/canccolrectgen/canccolrectgen.html NHHS|http://www.virtuallaboratory.net/Biofundamentals/lectureNotes/AllGraphics/slippage.jpg NHHS|http://www.exactsciences.com/pregen26/professionals/about_hnpcc/_index.htm NHHS|http://www.healthsystem.virginia.edu/uvahealth/hub_cancer/hnpcc.cfm NHHS|http://www.ohsu.edu/tech-transfer/technologies/wct_389.shtm NHHS|http://www.kimmelcancercenter.org/kcc/HereditaryCancer/HNPCC/hnpcc.htm NHHS|http://www.clevelandclinic.org/registries/inherited/hnpcc.htm NHHS|http://ghr.nlm.nih.gov/gene=mlh1 NHHS|http://www.ncbi.nlm.nih.gov/entrez/query.fcgi NHHS|http://www.mdc-berlin.de/~gfactor/maus.jpg NHHS|/courses/2005Spring/Biol169/ NHHS|http://my.webmd.com/hw/colorectal_cancer/nord953.asp

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