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PsaA. PsaA. PsaA+BLyS. PsaA+BLyS. PsaA-BLyS. PsaA-BLyS. PsaA+CFA. PsaA+CFA. -20. 0. 20. 40. 60. 80. 100. 120. 140. Cytokine spots/10 6 splenocytes. Cytokine spots/10 6 splenocytes. ASC. PsaA. PsaA+BLyS. PsaA-BLyS. PsaA+CFA. 0. 50. 100. 150. 200. 250.
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PsaA PsaA PsaA+BLyS PsaA+BLyS PsaA-BLyS PsaA-BLyS PsaA+CFA PsaA+CFA -20 0 20 40 60 80 100 120 140 Cytokine spots/106 splenocytes Cytokine spots/106 splenocytes ASC PsaA PsaA+BLyS PsaA-BLyS PsaA+CFA 0 50 100 150 200 250 PsaA-specific Igspots/106 splenocytes -50 0 50 100 150 200 IL-2 IFN- IL-5 IL-4 A PsaA-specific IgG subclass responses PsaA-specific recall responses by ELISPOT B Immunogens Immunogens Immunogens