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Effects of CCh and Cs+ on M1R and M3R Responses in C1α/5 Mutant Models

This figure illustrates the experimental results of cholinergic stimulation (CCh) at 100 µM and varying concentrations of cesium (Cs+) at 140 mM on M1R and M3R receptors in C1α/5 mutant models. The data emphasizes how changes in Cs+ concentration influence the receptor's response to CCh, highlighting alterations in signaling pathways. Comparative analysis includes the wild-type and C1αDN strains, providing insights into receptor interactions and functional impacts in cellular environments.

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Effects of CCh and Cs+ on M1R and M3R Responses in C1α/5 Mutant Models

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  1. Supplementary Figure 2 b. a. CCh Cs+ C1α/5 + M1R C1α/5 + M3R CCh (100M) Cs+ (140mM) CCh (100M) Cs++CCh d. c. Cs++CCh Cs++CCh CCh CCh C1αDN/5 + M1R C1αDN/5 + M3R CCh (100M) CCh (100M) Cs+ (140mM) Cs+ (140mM)

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