Competency 5. Cloning DNA Fingerprinting Karyotypes Genetics Pedigrees Mutations. What was Dolly?. Dolly the sheep was successfully cloned in Britain in 1996 by the scientist “Ian Wilmut ” and was put down in February 2003 after developing a lung infection and arthritis .
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of an adult animal.
Blood sample from crime scene
DNA is negatively charged so it is attracted to the positive end of the gel.
The shorter DNA fragments move faster than the longer fragments.
DNA is separated by size.
Material is swapped with another chromosome
(cancer of the lymph nodes, in children)
a segment of genes flip end-to-end on the chromosome
(cleft pallate, club feet, testes don’t descend)
A segment of genes is copied twice and added to the chromosome
(high arched foot, claw feet, confined to a wheelchair)
One or more genes are removed
Wolf-Hirschhorn syndrome (severe mental retardation)
cri du chat syndrome (mewing sounds, mental retardation)
Disorder: Trisomy: Definition:
Cystic Fibrosis #7 Mucus accumulate in the lungs
Edward’s Syndrome #18
Down’s Syndrome #21
Patau’s Syndrome #13
Sex linked Traits