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ADENOSINE PowerPoint Presentation

ADENOSINE

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ADENOSINE

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  1. O2 uric acid Xanthine Oxidase inosine Adenosine deaminase cAMP Inhibition by pentostatin ATP ADP AMP myocyte or parenchymal cell membrane macrophage modulation LPS (-) LPS ? NO-dependent Neutrophil Adenosine deaminase Inhibition IL-10 (+) (-) O2 ? cNOS NO-independent (+) IL-1ß TNF-alpha inosine adenosine iNOS vasodilation receptor Xanthine Oxidase O O 2 2 free radicals free radicals uric acid adenosine kinase ADENOSINE 5' nucleotidases ADENOSINE