This lesson will increase your knowledge of concepts covered in the following TEKS for biology:
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This lesson will increase your knowledge of concepts covered in the following TEKS for biology:. 3.c – Evaluate impact of research on scientific thought, society, and the environment 3.e – Evaluate models according to their adequacy in representing biological objects or events

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This lesson will increase your knowledge of concepts covered in the following TEKS for biology:

3.c – Evaluate impact of research on scientific thought, society, and the environment

3.e – Evaluate models according to their adequacy in representing biological objects or events

3.f – Research and describe the history of biology and contribution of scientists

5.a – Compare cells from different parts of the plant and animal

5.b – Identify cell differentiation in the development of organisms

10.a – Interpret the functions of systems in organisms

10.b – Compare the interrelationships of organ systems to each other and to the body as a whole


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Previous Lesson in the following TEKS for biology:Prostate Cancer


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QUESTION: in the following TEKS for biology: A vasectomy involves cutting pieces out of both vas deferens. Why does a vasectomy result in sterility?

Based on: Farish, D. Human Biology, Jones and Bartlett



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QUESTION: deferens to urethra LH-RH blockers are used to treat prostate cancer. How would this treatment control prostate cancer?


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Blocking LH and RH prevents the testes from receiving the messages to make testosterone

Male Hormones

Based on: Mader, S. Inquiry Into Life, McGraw-Hill


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QUESTION: messages to make testosterone What are the advantages and disadvantages of PSA tests for older men?


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Advantage of PSA test messages to make testosterone

Stages of Prostate Cancer

PSA + needle biopsy detects cancer when only a few cells are present so treatments are more successful

Based on: Mayo Clinic Health Letter, April 1985


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May detect tiny slow growing prostate cancers that would not affect the health of men over 80 causing needless worry and treatment

Disadvantage of PSA test


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Today’s Lesson affect the health of men over 80 causing needless worry and treatmentHuman Development and Stem Cells


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Overview of Lesson affect the health of men over 80 causing needless worry and treatment

  • Life cycle and development of humans

  • Miracle of Life video

  • Infertility and in vitro fertilization

  • Stem cells


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Life Cycle of Humans affect the health of men over 80 causing needless worry and treatment

Fig. 5.15

Based on: Mader, S. Inquiry Into Life, McGraw-Hill


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Human Development Involves affect the health of men over 80 causing needless worry and treatment

  • Addition of more cells through mitosis

  • Creation of adult cells with special functions through cell differentiation, creating about 210 different tissues in the body


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Mitosis of Body Cells affect the health of men over 80 causing needless worry and treatment

  • Prior to mitosis, replication of all 46 chromosomes forming 46 replicated chromosomes

    • Chromosome before replication

    • Replicated chromosome with two sister chromatids

  • Splitting of replicated chromosomes

  • Formation of two daughter cells with 46 chromosomes like the original cell


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Mitosis of Body Cells affect the health of men over 80 causing needless worry and treatment

Based on: Mader, S. Inquiry Into Life, McGraw-Hill


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Stages of Mitosis affect the health of men over 80 causing needless worry and treatment

Based on: Mader, S. Inquiry Into Life, McGraw-Hill


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Human Development To Implantation affect the health of men over 80 causing needless worry and treatment

Based on: Mader, S. Inquiry Into Life, McGraw-Hill


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Cell Differentiation affect the health of men over 80 causing needless worry and treatment

  • DNA directs changes in cells from a general cell type (embryonic stem cells) to specialized cell types in the adult

  • Until recently, scientists thought that once cells became specialized in the adult, the DNA could not be reprogrammed back to its undifferentiated state

Based on: Scientific American, June 2004


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Example of Adult Cell with Specialized Function affect the health of men over 80 causing needless worry and treatment

Nerve Cells

Based on: Mader, S. Inquiry Into Life, McGraw-Hill


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Example of Adult Cell with Specialized Function affect the health of men over 80 causing needless worry and treatment

Muscle Cell

Based on: Mader, S. Inquiry Into Life, McGraw-Hill


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Overview of Lesson affect the health of men over 80 causing needless worry and treatment

  • Life cycle and development of humans

  • Miracle of Life video

  • Infertility and in vitro fertilization

  • Stem cells


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Excerpt from affect the health of men over 80 causing needless worry and treatment

The Miracle of Life

Nova


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Overview of Lesson affect the health of men over 80 causing needless worry and treatment

  • Life cycle and development of humans

  • Miracle of Life video

  • Infertility and in vitro fertilization

  • Stem cells


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Infertility In Women affect the health of men over 80 causing needless worry and treatment

  • Hormone imbalance

  • Blocked fallopian tube

  • Ovarian cysts

  • Endometriosis

  • Uterine cysts


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Infertility In Men affect the health of men over 80 causing needless worry and treatment

  • Low sperm count

  • Weak sperm

  • Impotence

  • Hormone imbalance

  • Medication side effects


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In Vitro Fertilization (Test Tube Baby) affect the health of men over 80 causing needless worry and treatment

  • Hormones given to woman to stimulate eggs

  • Eggs harvested from ovary

  • Eggs fertilized with man’s sperm in glass container

  • Embryos allowed to develop for a few days

  • Embryos implanted in uterus and allowed to develop for 9 months

  • Extra embryos are frozen for later attempts if first attempt fails


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Louise Brown, the first “test-tube baby” affect the health of men over 80 causing needless worry and treatment

From Time, December 1, 1997


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Overview of Lesson affect the health of men over 80 causing needless worry and treatment

  • Life cycle and development of humans

  • Miracle of Life video

  • Infertility and in vitro fertilization

  • Stem cells


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Dr. James Thomson affect the health of men over 80 causing needless worry and treatment

University of Wisconsin

  • in 1998, collected stem cells from surplus embryos created at fertility clinics

  • stopped stem cells from differentiating

  • kept them alive and reproducing indefinitely

Click on URL below to upload cover of TIME

TIME Magazine Cover: Scientist James Thomson - Aug. 20, 2001


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Source of Stem Cells affect the health of men over 80 causing needless worry and treatment

Based on: Scientific American, June 2004


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Potential of Stem Cell Research affect the health of men over 80 causing needless worry and treatment

Based on: Time, July 23, 2001


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Against Funding Research affect the health of men over 80 causing needless worry and treatment

From: Time, July 23, 2001

For Funding Research

From: Time, July 23, 2001


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Fate of Stem Cell Research Funding? affect the health of men over 80 causing needless worry and treatment

From: Time, July 23, 2001

  • 2000 President Clinton stated only embryos from fertility clinics and in excess could be used for research

  • 2001 President Bush banned federal funds for stem cell research except on stem cell lines already cultured in labs- 78 lines

  • 2003 European Parliament voted in Brussels to support funding of stem cell research


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Fate of Original 78 Stem Cell Lines affect the health of men over 80 causing needless worry and treatment

  • 1 still under development

  • 1 donor consent withdrawn

  • 7 duplicates of other cultures

  • 16 died after being thawed

  • 31 are at overseas labs unavailable to U.S.

  • 21 viable stem cell lines remain in U.S.- aging, limited in genetic diversity, hinderance

Time 2006 http://www.time.com/time/magazine/article/0,9171,1220538-2,00.html


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Why a fight over federal funding? affect the health of men over 80 causing needless worry and treatment

  • Federal funding drives the speed of research progress

  • Without federal funding, the U.S. could slip behind in the biotechnology race


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What are the sources? affect the health of men over 80 causing needless worry and treatment

Based on: Mader, S. Inquiry Into Life, McGraw-Hill

  • Embryonic stem cells

  • Adult stem cells

  • Nuclear-transfer embryos

  • Umbilical-cord blood and placental cells


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Next Lesson affect the health of men over 80 causing needless worry and treatment

DNA and the Human Genome Project