Plasma Exchange consists of the removal of large volumes of the patient' s plasma and replacing it with exogenous plasma or plasma substitutes Action: removes from the circulation any pathogenic material decrease T lymphocytes (indirect action) normalize abnormal T4/T8 ratio (indirect).
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In 10 Pxs with PG treated with plasma exchange once to three times weekly for a total of 4 to 27 exchanges
- (7) excellent response
- (3) incomplete or no response
* When used at the higher doses, IVIG possesses immunosuppressive activity through poorly understood mechanisms.