Development of Customized Heart Valves from Bovine Pericardium

1. Development of Customized Heart Valves from Bovine Pericardium Medical technology has advanced to an extent that it is possible to create heart valves and transcatheter using pericardium tissue from bovine species. The lab tested and research tissue is 100% safe for use with accurate prototyping as well as product designing. The size and specifications can be customized as per requirement. The bovine pericardium tissue is biocompatible for production of the valves with use of the tissue from scratch. This has helped people with cardiovascular disease to recover from multiple conditions. The clinical trials and extensive research has led to development of safe tissue patches for production of transcatheter aortic, mitral, and tricuspid valve. End to End Delivery of Services for Heart Tissues The tissue manufacturing companies provide comprehensive service right from procuring the right tissue from either bovine or porcine source. However, bovine is considered the most feasible option for the ease of production of valves using the same. After the procurement, there is test conducted for monitoring any disease.

2. The tests are conducted as per standard protocol in state of the art lab. The testing helps in studying and identifying the presence of any disease and hence monitors the standard of the tissue. This prevents complications that may arise from it. The raw tissue cannot be used and hence it must be effective fixed with certain products or reagents to make it suitable for use. Tissue fixation method is quite crucial and post that risk assessment must be conducted as per FDA compliance. Once the tissue patch is good for use and passed all the tests, it is designed and prototyped to custom design heart valves. The anti-calcification method is quite crucial for design the valve using the tissue and tests must be conducted for viral inactivation. There is complete study and analysis conducted on the tissue patch before it is further processed into the construction of the valves. This is an important step as without the testing, it might lead to adverse impact. The test is conducted by professional medical experts. Use of Bovine Pericardium for Construction of Heart Valve Pericardium is a double membrane tissue of heart which is harvested and processed for production of heart valves and transcatheter due to its higher biocompatibility. The bovine tissue patch for heart valve is quite common as it has higher strength and elasticity with high collagen protein. The pericardium from bovine is suitable for heart conditions as it perfectly fits the requirement of the human heart valves. The design and prototyping helps in production of stent as per the requirement of the patient. After that, the valve from bovine pericardium is sewed around the stent. Advance Prototyping and Designing of Cardiovascular Valves For the heart valves, the bovine pericardium after going through multiple stages of testing and processing is prepared according to the stent. The skilled technicians and researchers help in biocompatibility test so that the body does not reject the pericardium. Each of the valves and its size and prototype is customized. The thickness and size of the tissue can be altered depending on the customer.