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Anthrax is caused by the gram-positive aerobe Bacillus anthracis, which primarily infects herbivores like cattle and sheep through spores. These spores are resilient and can survive for years. The disease manifests in three forms: cutaneous, inhalation, and gastrointestinal, depending on exposure. In 2001, anthrax was used as a biological weapon in the U.S., leading to fatalities and highlighting its potential as a bioterrorism agent. Understanding its methods of infection, toxic effects, and historical uses is crucial for public health and safety.
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Bio II Do Now Please copy the following information into your notes: Anthrax Causative organism: Bacillus anthracis, gram + aerobe Infection method: Spores (not person-person) Natural hosts: herbivores (cattle, sheep, etc.) Disease: lungs, skin, or digestive tract, depending on exposure. Biological Warfare: Dangerous bio-weapon responsible for 2001 anthrax attacks in US
SPORES! • Spores are like bacteria seeds. They are tough, inactive cells that can survive for decades or centuries. Many Bacillus species form spores
Disease Method: exotoxins • Bacillus anthracis produces toxic chemicals that kill nearby cells Cutaneous (skin) anthrax
Biological Warfare • Studied and used by US, UK, USSR, and German armies in the past. • Weaponized versions are antibiotic resistant, highly deadly, and have fine spores that stay airborne for long periods of time.
Terrorist Threat • The US anthrax attacks of 2001 used a military weapon strain from an Army research lab. 5 people were killed in what was the most extreme example of domestic bio-terrorism to date.