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What you need to know about: Bone Cancer - PowerPoint PPT Presentation


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What you need to know about: Bone Cancer. By: Mrs. Boggs. Bone Cancer. Bone cancer is cancer that arises first in the bone. True bone cancer is called osteosarcoma Bone is often a secondary site of metastases for other types of cancer such as prostate cancer, lung cancer, breast cancer, etc.

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Presentation Transcript
bone cancer
Bone Cancer
  • Bone cancer is cancer that arises first in the bone.
  • True bone cancer is called osteosarcoma
  • Bone is often a secondary site of metastases for other types of cancer such as prostate cancer, lung cancer, breast cancer, etc.
risk factors
Risk Factors
  • The exact cause for bone cancer is not known, but there are many risk factors for the disease; some can be avoided while others can not.
  • Risk factors include:
    • Smoking
    • Age
    • Race
    • Having other diseases such as retinoblastoma
    • Treatment with radiation
biology of cancer
Normal Cell Cycle

Cancer Cell Cycle

Divide without appropriate signals

Can continue growing even though they are in contact with other cells

Cells continue through the cell cycle without the “all clear” signal from the checkpoint regulators

Biology of Cancer
dna damage
One of the leading causes of bone cancer is radiation

Radiation results in:

Point mutations

Chromosomal damage

Break DNA

DNA Damage
  • Point mutations occur when bases in DNA are changed
  • There are different types of point mutations including:
    • Nonsense
    • Missense
    • Frameshift
treatment
Surgery

Removes the tumor mass from initial location

Radiation Therapy

Uses high energy waves targeted to cancer growth

Waves cause damage within the cell, disrupt cellular processes, prevent accurate cell division, and cause the cell to die

Death of cells causes the tumor to shrink

Treatment
prevention
Prevention
  • There is way to truly prevent bone cancer
  • General cancer preventions include:
    • Diets low in fat
    • Exercise
    • Eat lots of fruits and vegetables
    • Do not smoke
    • Limit consumption of alcoholic beverages
    • Limit UV radiation