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Chem150 - Survey of Biochemistry

Chem150 - Survey of Biochemistry

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Chem150 - Survey of Biochemistry

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  1. Chem150 - Survey of Biochemistry • Introduction

  2. Introduction • The chemistry we will focus on this semester • Organic Chemistry • The chemistry of carbon • Functional groups • Biochemistry • The chemistry of living systems

  3. Organic Chemistry

  4. Organic Chemistry • Hydrocarbons represent the starting point • Contain only carbon and hydrogen • Groups include Alkanes, alkenes and alkynes Butane

  5. Organic Chemistry • Organic molecule are organized into functional groups • Many contain elements other than carbon and hydrogen • Oxygen • Nitrogen • Sulfur • Halogens (F, Cl, Br, & I)

  6. Organic Chemistry

  7. Organic Chemistry • Functional Groups • Hydroxyl groups (alcohols) Hydroxyl Group 1-Butanol

  8. Organic Chemistry • Functional Groups • Amino groups (amines) Amino Group 1-Butylamine

  9. Organic Chemistry • Functional Groups • Carbonyl groups (aldehydes and ketones) Aldehyde Group Butanal

  10. Organic Chemistry • Functional Groups • Carboxyl groups (carboxylic acids) Carboxyl Group Butanoic acid

  11. Organic Chemistry • Functional Groups • Functional group affect the physical and chemical properties of organic molecules. Butane (alkane) Butanol (alcohol) Butylamine (amine) Butanoic acid (carboxylic acid) water Butanal (aldehyde)

  12. Organic Chemistry • Functional Groups • chemical structure affects drug or hormone-receptor interactions

  13. Organic Chemistry • Functional Groups • Is this even possible? Or this? http://www.ftc.gov/opa/2008/08/airborne.shtm http://www.ftc.gov/opa/2007/08/hoodia.shtm

  14. Survey Question (Clicker) • Do you think there is some validity to HeadOn as a headache cure? • Yes • No • I don’t know What chemical questions would you want to have answered to decide ?

  15. Survey Question (Clicker) • Do you have concerns about Nalgene bottles and health risks (esp to babies)? • Yes • No • I don’t know What chemical questions would you want to have answered to decide ?

  16. Nalgene polycarbonates What chemical questions would you want to have answered to decide ?

  17. ORGANIC MOLECULE IN THE NEWS: Bisphenol A

  18. PHARMACOPHORE IN THE NEWS: Bisphenol A http://e.hormone.tulane.edu/learning/estrogens.html

  19. Biochemistry • Biological molecules • Amino acids and Proteins • Carbohydrates and Polysaccharides • Nucleotides and Nucleic acids • Lipids (Fats, oils)

  20. Biochemistry • Biological molecules • Aminoacids and Proteins Carboxylic Acid Group Amino Group Alanine

  21. Biochemistry • Biological molecules • Carbohydrates and Polysaccharides Glucose

  22. Biochemistry • Biological molecules • Lipids (Fats, oils) Triglyceride

  23. Biochemistry • Biological Macromolecules • Proteins, Polysaccharides and Nucleic Acids • Metabolism • Taking things apart • Putting things together • Obtaining and using energy • Regulation of processes.