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SURVEY OF BIOCHEMISTRY Fatty Acid Oxidation

SURVEY OF BIOCHEMISTRY Fatty Acid Oxidation. Overview of Lipid Metabolism. Triglyceride Breakdown. Triglycerides break down into 3 fatty acids and one molecule of glycerol. Activation of Fatty Acids Acyl-CoA Synthetase. Step 1. Activation of Fatty Acids Acyl-CoA Synthetase. Step 2.

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SURVEY OF BIOCHEMISTRY Fatty Acid Oxidation

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  1. SURVEY OF BIOCHEMISTRYFatty Acid Oxidation

  2. Overview of Lipid Metabolism

  3. Triglyceride Breakdown • Triglycerides break down into 3 fatty acids and one molecule of glycerol.

  4. Activation of Fatty AcidsAcyl-CoA Synthetase Step 1

  5. Activation of Fatty AcidsAcyl-CoA Synthetase Step 2

  6. Carnitine as a Carrier

  7. Carnitine as a Carrier

  8. Fatty Acid OxidationSaturated Fatty Acyl-CoA

  9. Fatty Acid OxidationStep 2

  10. Fatty Acid OxidationStep 3

  11. Fatty Acid OxidationStep 4

  12. Examples of Unsaturated Fatty Acids

  13. Oxidation of Unsaturated Fatty Acids

  14. Oxidation of Unsaturated Fatty Acids

  15. Oxidation of Unsaturated Fatty Acids

  16. Oxidation of Unsaturated Fatty Acids Moves the double bond!

  17. Another Problem in Oxidizing Unsaturated Fatty Acids Poor substratefor enoyl-CoA hydratase

  18. Alternative Pathway for Unsaturated Fatty Acids Study Figure 20-12 and Figure 20-15

  19. Odd-Chain Fatty Acids

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