Mathieu Orfila Father of Toxicology. Disease Informatics: Living in the toxic world. Toxins are component causes of most of the diseases and hence detoxification is usually beneficial. “Clean bowled is not the complete cricket”.
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Father of Toxicology
Toxins are component causes of most of the diseases and hence detoxification is usually beneficial
“Clean bowled is not the complete cricket”.
Similarly, diseases are complex. IT applications can handle disease data complexities and could provide better definition of diseases.
Presentation by R.P.Deolankar
“toxico- “ is a root of a word meaning poison or toxin.
Hormones and neurotransmitters keep harmony with each other, body systems and nature’s circadian rhythms. Loss of the harmony causes several disorders.
Abnormal neuroendocrine-response leads to
Protection of enkephalins (neurotransmitters) by enkephalinase inhibitors causes reversal of diarrhea associated with infectious agents like rotavirus. What disrupts function of enkephalins?
Toxic air groundwaterAir pollution
Intoxicating habits groundwaterAlcohol: Intoxicating ingredient of many common beverages
Toxic foods groundwaterRefined white sugar
Toxic environment groundwaterAluminiumutensils and acidic water
Oxygenation (Cytochrome p450 system) and conjugation (sulfate, glutathione and glucuronic acid, glycine, taurine etc) and methylation are detoxifying functions of liver.
Increase in intestinal bacteria producing deconjugating enzymes results in reabsorption of estrogen through enterohepatic circulation. The excess of the hormone could be associated with the disease like breast cancer. Probiotic lactobacillus reduce deconjugating bacteria thereby help in prevention of the cancer.
Indole-3-carbinol, possibly anticarcinogenic, antioxidant, and anti-atherogenic compound, occurs naturally in cruciferous vegetables such as cabbage, broccoli, brussels sprouts, and kale.
Limonene present in citrus peels and rind dissolves cholesterol, normalizes peristalsis and reduces heart burn; considered as detoxifying agent.
Spa therapies groundwaterCleaning through gut
Clothing, particularly tight undergarments, obstruct lymph movement and detoxification process
Tools for study groundwaterToxicological signatures
Organizations and databases groundwaterOECD
Toxicogenomics: A study of the response of a genome to hazardous substances, using “omics” technologies
Providing tools for:
The lecture series is being prepared for IT specialists and health workers who would team up to solve the disease problems.
Agada Tantra of Ancient Indian medicine is Toxicology