Drosophila Genomics Resource Center. Justen Andrews Peter Cherbas http://dgrc.cgb.indiana.edu/. Drosophila Genomics Resource Center. Clones/vectors/RNAi/2-hybrid collection ~300,000, distribution >3,000 Cell lines collection ~ 100, distribution >200 Microarrays
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of the transcriptome: the big picture
Where are all the transcription units, what are all the splice variants, in which cells are they expressed?
Where are all the cis-regulatory sequences, what are the corresponding trans-factors, what is the regulatory network diagram through space and time?
The solution is going to include a range of integrated experimental and computational approaches (comparative sequence analysis, transcriptional profiling, chip-chip) spanning a range of organizational levels (centers, consortia, individual labs).
genome tiling path
J Tim Westwood