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HERBS

HERBS . Lisa Meister February 27, 2009. 1. Objective. Discuss common uses of herbal remedies that are popular in Mexican culture Review of the “evidence” Develop awareness of potential adverse reactions and/or drug interactions Will talk about Nopal, Aloe, Chamomile and Peppermint. 2.

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HERBS

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  1. HERBS Lisa Meister February 27, 2009 1

  2. Objective • Discuss common uses of herbal remedies that are popular in Mexican culture • Review of the “evidence” • Develop awareness of potential adverse reactions and/or drug interactions • Will talk about Nopal, Aloe, Chamomile and Peppermint 2

  3. Nopal Opuntia ficus indica, streptocantha, etc. 3

  4. Uses 4 • Diabetes • Hypercholesterolemia • Obesity • Alcohol-induced hangover • Colitis • Diarrhea • BPH • Atherosclerosis

  5. 5 Nopal’s Active Components • Fibrous Polysaccharide (Fiber) • Pectin

  6. 6 The Evidence • decreases in LDL, TGs, while HDL unchanged. • Hypoglycemic effects as well as increases in insulin sensitivity • BPH? • Anti-inflammatory- Alcohol Hangover study

  7. Adverse Effects 7 • Diarrhea, nausea, increased stool volume and/or frequency, abdominal fullness and headache • If already taking hypoglycemic drugs, watch out for hypoglycemia

  8. 8 Aloe Vera

  9. Uses 9 • Ulcerative Colitis, ulcers, constipation, colitis, laxative • Osteoarthritis, bursitis • Diabetes • Asthma, psoriasis • Cold sores, radiation related mucositis, burns, sunburn, frostbite, wound healing • Epilepsy • Bleeding • Varicose veins

  10. Aloe’s active ingredients • Emodin anthrone • Dithranol • Chrysarobin • Carboxypeptidase • Magnesium lactate • C-glucosyl chromone • Salicylate • Allantoin • Aloe Latex (Anthraquinone family) 10

  11. The Evidence • Plaque Psoriasis • Decreases serum blood glucose • Lichen planus 11

  12. Adverse Effects • Topical- allergic reaction, delay in surgical wound healing • Oral- hypoglycemia, hypokalemia, bleeding, uterine contractions 13

  13. Chamomile Matricaria recutita, chamomila

  14. Uses • GI: Flatulence, nervous diarrhea, spasms, colitis, gastritis, hemorrhoids • Nasal mucus membrane inflammation • Allergic rhinitis • ADHD • Restlessness, insomnia • Dismenorrhea • Mastitis • Varicose ulcers 14

  15. Active Ingredients • Quercetin • Apigenin • Coumarins • Essential oils: matricin, chamazulene, alpha bisaboloid, bisaboloid oxides 15

  16. The evidence • Dyspepsia • Oral mucositis • Eczema 16

  17. Adverse reactions • Allergic reactions, including anaphylaxis, allergic conjunctivitis, contact dermatitis • Drug interactions 17

  18. Peppermint Mentha Piperita 18

  19. Uses • Common cold • Inflammatory processes of mouth, sinuses, pharynx, liver, gallbladder and bowel • Nausea, vomiting, dyspepsia • Headache • Morning Sickness • Dismenorrhea 19

  20. Active Ingredients • Acetaldehyde • Amyl alcohol • Menthyl esters • Limone • Pinene, etc. etc. etc. 20

  21. The evidence • Irritable bowel syndrome • Dyspepsia • Barium enema related colonic spasm 21

  22. Adverse effects • Heartburn, nausea, vomiting • Allergic reactions • Flushing • Headache • Hepatotoxicity at high doses • P450 inhibitors • Testosterone may decrease • amphB 22

  23. The end

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