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Biocompatible Bone Fillers

Biocompatible Bone Fillers. Pelvic Osteolysis Felicia Shay Computer Integrated Surgery II. Bone Filler Ingrowth . Bibliography: Papers.

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Biocompatible Bone Fillers

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  1. Biocompatible Bone Fillers Pelvic Osteolysis Felicia Shay Computer Integrated Surgery II

  2. Bone Filler Ingrowth

  3. Bibliography: Papers • S. Takaaki, M. Saito, K. Kawagoe, et al. “New hydroxyapatite composite resin as a bioactive bone cement: improvement of handling and mechanical properties.” Bioceramics. Vol. 11 (1998): World Scientific Publishing Co. Pte. Ltd, 251-254. • W. F. Mousa, M. Kobayashi, S. Shinzator, et al. “Biological and mechanical properties of commercial PMMA bone cements containing AW-GC filler” Bioceramics. Vol. 12 (1999): World Scientific Publishing Co. Pte. Ltd, 545-548. • Y. Okada, K. Kawanabe, H. Fujita, et al. “Bonding behavior of bioactive bone cement in segmental replacement of rabbit tibia: comparison with PMMA bone cement.” Bioceramics. Vol. 12 (1999): World Scientific Publishing Co. Pte. Ltd, 529-533.

  4. Bibliography: Continued • N. Asaoka, M. Misago, M. Hirano, et al. “Mechanical and chemical properties of the injectable calcium phosphate cement.” Bioceramics. Vol. 12 (1999): World Scientific Publishing Co. Pte. Ltd, 525-528. • F.C.M. Dreissens, M.G. Boltong, E.A.P. de Maeyer, et al. “Comparative Study of Some Experiemental or Commercial Calcium Phosphate Bone Cements.” Bioceramics. Vol 11 (1998): World Scientific Publishing Co. Pte. Ltd, 231-234

  5. Test Materials/Composition • PMMA • PMMA Composites • Bioglass • PMMA/ Ca/P Composites • Ca/P Composites • Hydroxyapatite

  6. Background • Fundamental of: • PMMA • Ca/P • Bioglass • Uses • Ideal

  7. Methods of Testing • Cyclic Wear: Compression • Tension: Figure 1 • X-ray Diffraction: Analyze reaction • Scanning Electron Microscope (SEM): Microstructure • Injectability • Setting time

  8. Comparison of Ca/P Materials

  9. Compressive Strength

  10. Bioactive vs PMMA: after time

  11. PMMA in Rat Tibia: 8 weeks

  12. Weaknesses • Lack of: • In vivo testing for some experiences • Long term testing for analysis • Testing of different porousity • Uniform testing for all types of materials • Dependency upon: • Mixing • P/L ratio dependent

  13. Strengths • Uniform Testing methods • In vivo like environments • Good comparison of materials • Length of testing • Different: • Composites • P/L ratios

  14. Results/Discussion • Results • Interpretation • Inconsistencies • Overlapping • Resolution • Additional studies

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