trait and sex selection the arrival of non invasive prenatal genetic testing
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Trait and Sex Selection: The Arrival of Non -Invasive Prenatal Genetic Testing. Jaime King, JD, PhD University of California, Hastings College of the Law Tarrytown Meeting July 26, 2011. Contents of Maternal Blood Serum. Non-Invasive Prenatal Diagnosis. No Brave New World?.

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trait and sex selection the arrival of non invasive prenatal genetic testing

Trait and Sex Selection: The Arrival of Non-Invasive Prenatal Genetic Testing

Jaime King, JD, PhD

University of California, Hastings College of the Law

Tarrytown Meeting

July 26, 2011

critical features of nipd
Critical Features of NIPD
  • Non-Invasive
  • Timing
  • Comparatively Less Expensive
current prenatal genetic diagnosis
Current Prenatal Genetic Diagnosis

Amniocentesis

Chorionic Villus Sampling

non invasive prenatal diagnostic testing timeline
Non-Invasive Prenatal Diagnostic Testing Timeline
  • 4-5 Weeks - Earliest Detection of cell free fetal DNA (cff DNA)
  • 7-9 Weeks - Commercial Sex Determination
  • 9 Weeks - Reliable Genetic Testing
  • 7-10 Weeks - Reliable Aneuploidy Testing
current prenatal screening timeline
Current Prenatal Screening Timeline

Diagnostic Tests

- Chorionic Villus Sampling - 10-13 weeks

- Amniocentesis - 15+ weeks (preferred)

The California Prenatal Screening Program, Patient Booklet, March 2009

costs
Costs
  • T21 – Steven Quake predicts testing costs will be ~ $300 for Down Syndrome.
  • Prenatal Screening ~ $200
  • Ultrasound ~$300
  • Amniocentesis and CVS ~ $1500
major uses
Major Uses
  • Sex Determination
  • Diagnosis of Fetal Blood Type
  • Detection of Fetal Aneuploidy
  • Diagnosis of Single Gene Disorders
  • Susceptibility to Multigene and Complex Genetic Disorders
  • Genome Wide Analysis
who will offer nipd
Who will offer NIPD?

Physicians

Biotechnology Companies

Both?

longer term implementation concerns
Longer Term Implementation Concerns
  • Routinization of Prenatal Genetic Testing
  • Regulating Reproductive Autonomy
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