slide1 n.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
LIPID ANABOLISM PowerPoint Presentation
Download Presentation
LIPID ANABOLISM

Loading in 2 Seconds...

play fullscreen
1 / 71

LIPID ANABOLISM - PowerPoint PPT Presentation


  • 316 Views
  • Uploaded on

LIPID ANABOLISM. acetyl-CoA carboxylase. fig 21-1. acetyl-CoA carboxylase. fig 21-1. acetyl-CoA carboxylase. fig 21-1. condensation. fig 21-2. reduction. fig 21-2. dehydration. fig 21-2. reduction. fig 21-2. synthesis of fatty acids…. fig 21-4. synthesis of fatty acids….

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'LIPID ANABOLISM' - ziarre


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
slide1

LIPID

ANABOLISM

slide5

condensation

fig 21-2

slide6

reduction

fig 21-2

slide7

dehydration

fig 21-2

slide8

reduction

fig 21-2

slide12

acyl carrier protein

(ACP) in E. coli

a lot like…

fig 21-4

slide13

coenzyme A

fig 16-3

slide14

AcCoA-ACP

transacetylase

(AT)

fig 21-6 (4th)

slide15

malonyl-CoA-

ACP transferase

(MT)

fig 21-6 (4th)

slide16

b-ketoacyl-ACP

synthase (KS)

fig 21-6

slide17

b-ketoacyl-ACP

reductase (KR)

fig 21-6

slide18

b-hydroxyacyl-ACP

dehydratase (HD)

fig 21-6

slide19

enoyl-ACP

reductase (ER)

fig 21-6

slide20

acetylCoA-ACP

transacetylase (AT)

fig 21-6

slide23

fatty acid

synthases

variations

of the FAS

complex

fig 21-7

slide27

and a minor NADPH source…

majority supplied by

pentose phosphate p.way

fig 21-10

slide29

Phosphorylation of fatty acid synthesis

active un-phosphorylated ACC

makes cytosolic filaments

fig 21-11

slide30

now what…?

elongation

desaturation

fig 21-12

slide31

provided

by plants:

polyunsat.

fatty acids

fig 21-14.

slide32

cyclooxygenase

a key reaction

of inflammation in

mammals…

fig 21-15.

slide33

willow

bark

aspirin: a cycloxygenase inhibitor

fig 21-15.

slide36

Two COX isozymes

COX1

gastric

functions

COX2

inflammation

pain fever

box 21-2

slide40

lipid menagerie

phospholipid

triglyceride

slide41

phospholipids or glycerophospholipids

phophatidylcholine

phophatidylserine

slide42

mobilizing

glycerol

fig 21-17.

slide43

adding

acyl

groups

phosphatidic acid

a phospholipid

fig 21-17.

slide44

more

phospholipids

or glycerides…

fig 21-18.

slide46

another

trinucleotide-

based carrier:

CTP

slide48

The isoprene unit:

a branched lipid structure

slide50

four stages

of

cholesterol

synthesis

fig 21-33

slide51

four stages

of

cholesterol

synthesis

fig 21-33

slide52

four stages

of

cholesterol

synthesis

fig 21-33

slide53

stage 1

mevalonate

production

fig 21-34.

slide54

stage 1

mevalonate

production

fig 21-34.

slide55

stage 1

mevalonate

production

fig 21-34.

slide56

stage 1

mevalonate

production

fig 21-34.

slide57

first steps

of ketone

body

formation

synthesis

of

mevalonate

fig 21-34.

slide58

stage 2: conversion to

active isoprenes

fig 21-35

slide59

“tail”

“head”

condensation of isoprenes

fig 21-36.

slide64

LDL:

the

infamous

lipoprotein

fig 21-39.

slide68

regulation

of cholesterol

metabolism

both uptake

and synthesis

are involved

fig 21-44

slide70

sterols

galore!

fig 21-45

slide71

isoprenoids

galore!!

fig 21-47