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Irinotecan Leakage from Mo/Ma Cells: Quantification and Impact Study

This study investigates the leakage of irinotecan from Mo/Ma cells on days 0 and 2, calculating the loaded amounts and leaked quantities. The findings shed light on the drug release kinetics for potential therapeutic optimization.

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Irinotecan Leakage from Mo/Ma Cells: Quantification and Impact Study

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  1. Figure Legend Supplemental Figure 1: Irinotecan leaking: [A] Irinotecan fluorescence from Mo/Ma immediately after washing on day 0 (days since loading); [B] Irinotecan fluorescence from Mo/Ma on day 2; [C] Calculated amount of irinotecan loaded in the cells; and [D] Calculated amount of irinotecan leaked from the cells.

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