RABIES IMMUNOGLOBULINS. Dr.P.SANGRAM, MBBS, MD; MRC PATH (LONDON). Treatment of Rabies. WHO Recommendations ( based on category of dog bites) :. Treatment of Rabies. WHO Recommendations ( based on category of dog bites) :. WHO RECOMMENDS FOR ALL CATEGORY III EXPOSURES. Indication.
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Dr.P.SANGRAM, MBBS, MD; MRC PATH (LONDON)
Single or multiple transdermal bites or scratches
Contamination of mucous membrane with saliva (licks)
Rabies takes 20000 lives every year.
More than 70% victims are of category-III bites
Awareness of RIG is still poor
Only 6% victims gets complete treatment
20 Units per kg of body weight
40 Units per kg of body weight
Duration of Protective Effect:
Short: Rabies immunoglobulin has a half-life of approximately 21 days.
Cross sensitivity and/or related problems:
Patients sensitive to other human immune globulin products may be sensitive to Rabies Immunoglobulin also.
1) Mild Local Reaction: Anti histamines
2) Systemic reaction EPINEPHRINE 1:1000 (Aqueous) – 0.01ml / Kg per dose repeated every 10 – 20 minutes.
Infants – 0.05ml – 1ml
Children – 0.1 - 0.3 ml
Adolescents – 0.3 – 0.5 ml
3) SEVERE CASES:
HYDROCORTISONE : I.V 100 – 200 Mg / Kg
Provide Complete Treatment and
Protection against deadly Rabies
with ARV (Abhayrab) and RIG
(Abhay RIG) and save lives !!
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