ENDOMETRIAL HYPERPLASIA INCIDENCE. Arian Alikaj, Rubena Moisiu. Endometrial hyperplasia incidence.
Arian Alikaj, Rubena Moisiu
Study PopulationPatients presented to hospital aged 18-60 years with the complaint: Menometrorrhagia.The study was conducted in SUOGJ "Koco Gliozheni"The study of 993 patients biopsy taken during the years 2003-2006.The average age of patients was 43 years (18-60)The total number of hyperplasia is 270 (27%)Diagnosis is supported by endometrial biopsy. Biopsy were examined by an experienced anatomopatologo
Is often associated:
Polycystic ovary syndrome 54 (20%)
Obesity 37 (13.%)
Annovulation 77 (28.5%)
Diabetes 22 (8.1%)
Hormonal Therapy 5 (1.8%)
Infertility 23 (8.5%)
Tamoxifen use 18 (6.6%)
Incidence of progression to invasive carcinoma in
untreated endometrial hyperplasia
Simple hyperplasia 1%
Complex (adenomatous) hyperplasia <5%
Simple hyperplasia with atypia 5-10%
Complex (adenomatous) hyperplasia with atypia 25-30%
Endometrial hyperplasia incidence is higher among 50-60 years old women with peak age 54 years.
The incidence of atypical hyperplasia increases significantly after age 60 years.
Atypical hyperplasia is rare before age 30 years
Obesity and polycystic ovary favor endometrial hyperplasia
After age 30 years increases the frequency of endometrial hyperplasia with increasing probability every 5-years
Among women aged 18-30 years the incidence of simple hyperplasia is 58/100000 woman / Years