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ENDOMETRIAL HYPERPLASIA INCIDENCE. Arian Alikaj, Rubena Moisiu. Endometrial hyperplasia incidence.

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endometrial hyperplasia incidence

ENDOMETRIAL HYPERPLASIA INCIDENCE

Arian Alikaj, Rubena Moisiu

endometrial hyperplasia incidence1

Endometrial hyperplasia incidence

Study PopulationPatients presented to hospital aged 18-60 years with the complaint: Menometrorrhagia.The study was conducted in SUOGJ "Koco Gliozheni"The study of 993 patients biopsy taken during the years 2003-2006.The average age of patients was 43 years (18-60)The total number of hyperplasia is 270 (27%)Diagnosis is supported by endometrial biopsy. Biopsy were examined by an experienced anatomopatologo

endometrial hyperplasia incidence2
Endometrial hyperplasia incidence
  • Table 1 Classification of endometrial hyperplasia

(WHO,1994)

  • 1. Endometrial hyperplasia
  • a. Simple
  • b. Complex (adenomatous)
  • 2. Atypical endometrial hyperplasia
  • a. Simple
  • b. Complex (adenomatous with atypia)
endometrial hyperplasia incidence3
Endometrial hyperplasia incidence

Simple hyperplasia

Complex hyperplasia

Atypical hyperplasia

endometrial hyperplasia incidence4

Endometrial hyperplasia incidence

Is often associated:

Polycystic ovary syndrome 54 (20%)

Obesity 37 (13.%)

Annovulation 77 (28.5%)

Diabetes 22 (8.1%)

Hormonal Therapy 5 (1.8%)

Infertility 23 (8.5%)

Tamoxifen use 18 (6.6%)

endometrial hyperplasia incidence5

Endometrial hyperplasia incidence

Incidence of progression to invasive carcinoma in

untreated endometrial hyperplasia

Simple hyperplasia 1%

Complex (adenomatous) hyperplasia <5%

Simple hyperplasia with atypia 5-10%

Complex (adenomatous) hyperplasia with atypia 25-30%

endometrial hyperplasia incidence7
Endometrial hyperplasia incidence

Simple hyperplasia

Complex hyperplasia

Atypical hyperplasia

conclusions

Conclusions

Endometrial hyperplasia incidence is higher among 50-60 years old women with peak age 54 years.

The incidence of atypical hyperplasia increases significantly after age 60 years.

Atypical hyperplasia is rare before age 30 years

Obesity and polycystic ovary favor endometrial hyperplasia

After age 30 years increases the frequency of endometrial hyperplasia with increasing probability every 5-years

Among women aged 18-30 years the incidence of simple hyperplasia is 58/100000 woman / Years