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IGP - Cell Signaling Section 2004 Monday, February 9 10:00-11:00 am Lecture 2: Scaffold and Anchoring Proteins Brian

Signaling through scaffold, anchoring, and adaptor proteins. Protein modules for the assembly of signaling complexes. Modular domains recognizing specific sequences on their target acceptor protein are depicted.. Mechanisms for recruiting/localizing signal transduction complexes. (A) Assembly of modular signaling mole-cules on an activated receptor tyrosine kinase. (B) A localized signaling complex of three anchored signaling enzymes. Bound enzyme is usually inactive; in response to the appropriate signal, the enzyme is activated..

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IGP - Cell Signaling Section 2004 Monday, February 9 10:00-11:00 am Lecture 2: Scaffold and Anchoring Proteins Brian

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