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3S: Proteins

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  1. 3S: Proteins Shireen Rudina

  2. What do proteins do? • Structure • Collagen in skin, keratin in hair and nails • Signaling between cells • Defend against disease • Antibodies • Facilitate Reactions (enzymes) • Do essential work in each cell

  3. Which of these are proteins: • DNA • Fibers in your heart muscle • ? • ?

  4. Catalase is an enzyme 2H2O2 2H2O + O2 + heat Does not happen spontaneously, only in the presence of catalase.

  5. Important: Keeping your data organized!

  6. Peptide Bonds Connect Amino Acids

  7. Proteins are made of monomers called amino acids

  8. Polypeptide • Many amino acids connected by peptide bonds  polypeptides

  9. 20 amino acids

  10. Structural Activity

  11. Primary Structure • Order of amino acids linked together in a long chain • One end carboxyl & one end amino

  12. Secondary Structure • Chain of a.a.sbends based on the R groups Alpha helix or Beta pleated sheets

  13. Tertiary Structure • Further folding of the polypeptide chain • Disulfide bridges

  14. Quaternary Structure • Different polypeptide chains come together to form the final protein