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Bio 449 Lecture 13 - Endocrinology I Sep. 29, 2010

Bio 449 Lecture 13 - Endocrinology I Sep. 29, 2010. Readings Lectures 10-12: Chapter 10, pages 349- 379 Lectures 13- 14 : Chapters 6 & 7. Chemical messengers Classification of messengers Distance of travel Chemical structure Secreting tissue Hormone receptors

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Bio 449 Lecture 13 - Endocrinology I Sep. 29, 2010

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  1. Bio 449 Lecture 13 - Endocrinology I Sep. 29, 2010 Readings Lectures 10-12: Chapter 10, pages 349-379 Lectures 13-14: Chapters 6 & 7 • Chemical messengers • Classification of messengers • Distance of travel • Chemical structure • Secreting tissue • Hormone receptors • Control of hormone release • Hypothalamic-pituitary system • Structure • Hormones • Poterior pituitary • Anterior pituitary • Hypothalamus • Feedback control Terms to Know Exocrine glandEndocrine gland HormoneParacrine agentAutocrine agentCytokine Peptide hormoneSteroid hormoneAmineEicosanoid Prostaglandin Glandular hormoneNeurohormoneNeurosecretory cells ProhormoneTropic hormone

  2. Bio 449 Lecture 13 - Endocrinology I Sep. 29, 2010 More Terms Anterior pituitaryPosterior pituitary Follicle-stimulating hormone (FSH)Luteinizing hormone (LH)Growth hormone (GH)Thyroid-stimulating hormone (TSH)Adrenocorticotropic hormone (ACTH)Prolactin (PRL) Gonadotropin releasing hormone (GnRH)Growth hormone releasing hormone (GHRH)Thyrotropin releasing hormone (TRH)Corticotropin releasing hormone (CRH)Prolactin releasing hormone (PRH) aka Prolactin Releasing Factors (PRF) Growth hormone inhibiting hormone (GHIH)Prolactin inhibiting hormone (PIH, aka dopamine) Oxytocin (OT)Antidiuretic hormone (ADH, aka vasopressin)

  3. Types of glands

  4. Chemical messengers Classification of messengers

  5. Neurotransmitter Fig. 6-2

  6. Distance of travel

  7. Autocrine and paracrine agents Fig. 6-1

  8. Hormone Fig. 6-2

  9. Chemical structure

  10. Secreting tissue

  11. Neurohormone Fig. 6-2

  12. Chemical messengers Hormone receptors

  13. Membrane-bound receptors Fig. 6-5

  14. Intracellular receptors Fig. 6-4

  15. Control of hormone release

  16. Hypothalamic-pituitary system

  17. Hypothalamus and pituitary Fig.7-11

  18. Posterior pituitary HYPOTHALAMUS POSTERIOR PITUITARY Vein Fig.7-12

  19. Anterior pituitary HYPOTHALAMUS Neurons Capillary bed Artery Portal vessels POSTERIOR PITUITARY Endocrine cells Capillary bed ANTERIOR PITUITARY Veins TO TARGET ORGANS Fig.7-12

  20. Hypothalamic-pituitary system Hormonal pathways

  21. Hypothalamic-pituitary system Feedback control

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