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ASD calculation - PowerPoint PPT Presentation

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ASD calculation

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  1. ASD calculation Qp/Qs = (SaO2 – SvO2)/(PvO2-PaO2) SaO2 Systemic arterial O2 Saturation SvO2 Mixed Venous O2 PvO2 Pulmonary vein O2 saturation PaO2 Pulmonary Artery O2 saturation For ASD cases, Mixed venous O2 = (3SVC sat +1IVC sat)/4

  2. O2 Saturations: IVC 82% SVC 70% RA 85% PA 88% RV 84.5% Wedge 98.5% LV 97.5% LA 97% PvO2

  3. SaO2 = 97.5 • SvO2 = (3 x SVC + 1 x IVC) / 4 = (3 x 70 + 82) / 4 = 73 • PvO2 = 97.5 • PaO2 = 88 Qp/Qs = (SaO2 – SvO2)/(PvO2-PaO2) = (97.5 – 73)/(97.5 – 88) = 24.5/9.5 = 2.57

  4. J Thoracic Cardiovascular Surgery 1999; 118; 674-80

  5. 122 Patients Enrolled 14 Straight to Surgery 108 patients to attempted closure by device To Cath Lab 61 successful device closure 47 unsuccessful or not attempted due to: - large size of defect (27) -multiple defects (8) - location to close to other structures (11) Surgery

  6. JACC 2002; 39; 1836-44

  7. Procedure Success Rate: Device 96% vs Surgery 100% (p=0.006)

  8. Age range from few months to 82 years, significantly older in device group

  9. Total Complications: Device Group 7.2% (32) versus 24% (37), p<0.001