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Hierarchical Transmission of mRNA Layer Changes in Carbon Source Utilization

Explore the hierarchical transmission of mRNA changes in response to carbon source variation and stopping criteria using mathematical modeling. Analyze EFMs, flux, enzyme concentration, and mRNA levels.

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Hierarchical Transmission of mRNA Layer Changes in Carbon Source Utilization

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  1. P3 P4 I6 Hierarchical Transmission of changes in mRNA layer I2 Carbon Source A B2 I1 I4 B1 I5 I3 4 EFMs P2 P1 Carbon Source B P3 Stopping Criteria: R2≥ 0.60 0.80 <slope < 1.25 I6 I2 B2 I4 B1 I5 I3 P2 3 EFMs P1 r =f([A],[B],[E]) r A B Flux, r Enzyme, [E] mRNA

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