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DNA Replication Model

This DNA replication model illustrates the process of unzipping DNA strands by Helicase, forming nucleotides with nitrogenous bases, sugars, and phosphates. The replication process is explained for leading and lagging strands, involving DNA Polymerase III, Okazaki fragments, and Ligase to form phosphodiester bonds. The replication continues iteratively until completion, as shown in this detailed model.

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DNA Replication Model

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  1. DNA Replication Model By: Jacob Weaver Date: 2/6/14

  2. 3 A T 5 Key: Thymine Adenine G C Guanine Cytosine T A Sugar Phosphate G C A T Helicase This is a DNA Double Helix model. The A-Adenine, T-Thymine, G-Guanine, and C-Cytosine are the four nitrogenous bases in each strand of DNA. With a phosphate and a sugar makes a nucleotide. There is also a Helicase which unzips the DNA. There are 9 Adenine, Thymine, Cytosine, and Guanine bases and 9 Phosphates and sugars G C A T G C A T 3 5

  3. A T G C As the Helicase goes up through the stand of DNA is unzipping the strand. As it unzips the strand it is breaking the hydrogen bonds apart from each of the bases. T A G C A T Key: Thymine Adenine G C Guanine Cytosine A T Sugar Phosphate G C A T Helicase

  4. A T G This is showing how the hydrogen bonds are breaking as the Helicase is moving up through the DNA strand. C T A G C A T G C A T G C A T

  5. A T Key: Thymine Adenine G C Guanine Cytosine T A G C Sugar Phosphate T A Helicase G C A T G C T A

  6. A T Key: Thymine Adenine G C Guanine Cytosine T A Sugar Phosphate G C A T Helicase G C A T G C A T

  7. Key: A T Thymine Adenine G C Guanine Cytosine T A Sugar Phosphate C G Helicase A T G C A T G C A T

  8. A T Key: Thymine Adenine G C Guanine Cytosine A T G C Sugar Phosphate T A Helicase G C T A G C A T

  9. A T G C A T The Helicase finishing the dividing of the DNA strand. G C T A G C T A G C A T

  10. T A Then all the single strands, the Okarzki fragments and Ligase will form a phosphodiester bond. C G T Key: A Thymine Adenine C G Guanine Cytosine T A Sugar Phosphate C G Helicase A T T A G C G C T A T A G C A T G C A T

  11. T A On the left is the leading strand, which the bases are synthesized continuously. On the right is the lagging strand, where the bases are synthesized discontinuously . Which DNA polymer III adds five phosphate end of a free floating nucleotide to expose 3’ OH. C G T A C G T A T A G C C G A T T A G C G C T A A T T C T

  12. A T Which DNA polymer III adds five phosphate end of a free floating nucleotide to expose 3’ OH. This also occurs with the replication fork as well. G C A T G C C G A T A T C G G C T A T A G C C G A T A T

  13. A T G C A A T T G C C G A T A T Okazaki Fragments C G G C T A T A G C C G A T A T G C A

  14. A T T A G G C C A T T A G The lagging and leading have now completed the replication process. C G C A A T T C G C G T A T A G C C G A A T T

  15. A T T A The DNA replication continues like this until there is enough DNA made. G C G C A T T A G C G C A T A T C G C G A T T A G C C G A A T T

  16. The End of DNA Replication

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