1 / 7

Bioinformatics/HPC

Bioinformatics/HPC. Students Adda Zachary Deema Al Ghanim Horsley Jacqueline Sandrick Daniel. Mentors Xiaoming G ao Xinjun Zhang Thilina Gunarathne Supervised by Dr.Judy Qiu. Sequence Alignment. A way of arranging the biological sequences to identify regions of similarity

sydney
Download Presentation

Bioinformatics/HPC

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Bioinformatics/HPC Students Adda Zachary DeemaAl GhanimHorsley JacquelineSandrickDaniel • Mentors • XiaomingGao • XinjunZhang • ThilinaGunarathne • Supervised byDr.JudyQiu

  2. Sequence Alignment • A way of arranging the biological sequences to identify regions of similarity • Pairwise alignment • Find the best matching alignments of two query sequences • Multiple Sequence Alignment • Alignment of 3 or more biological sequences • Computationally difficult

  3. MDS Pairwise Sequence Alignment Sequences Dissimilarity Matrix Visualization Pairwise Clustering http://salsaweb.ads.iu.edu/salsa/

  4. Phylogenetics • Study ofevolutionaryrelatedness among various groups of organisms • Phylogenetic tree • Tree of life • Finding the correlations between Phylogenetic trees and the clustering approach

  5. Additional Software • PHYLIP (PHYLogenyInference Package) • Software available in IU Quarry • Inputs • Distance Matrix • Gene sequences • Clutalw • Available in IU BigRed • Multiple sequence alignment • Can generate data files for PHYLIP

  6. Thanks!!!

More Related