The Role of Glycolipid Transfer Proteins in the Intermembrane Transfer of Glycosphingolipids

Feb 07, 2026

50 likes | 187 Views

Glycolipid transfer proteins (GLTPs) play a crucial role in the intermembrane transfer of glycosphingolipids (GSLs), which are vital for cellular differentiation, growth, and signaling. With acyl chain lengths ranging from 16 to 24 carbons, these sphingosine-based GSLs regulate essential processes, including apoptosis and cell development. The structural dimers of GLTPs feature a head group recognition center, facilitating the effective transport and function of GSLs within membranes, thereby influencing various cellular outcomes.

sukey

Download Presentation

The Role of Glycolipid Transfer Proteins in the Intermembrane Transfer of Glycosphingolipids

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

GLTP GSL PART II. GLTPs(glycolipid transfer proteins) accelerate intermembrane transfer ofGSLs (glycosphingolipids) Acyl (16-24) sphingosine
GSLs (glycosphingolipids) are key regulators of cellular • differentiation • growth • development • signaling • apoptosis
sphingosine-out sphingosine-in
Dimers
GSL head group recognition center of GLTP