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Understanding Catabolic Pathways in Physiotherapy

This lecture series by Dr. Eman Mokbel Alissa focuses on the essential catabolic pathways vital for metabolism, bioenergetics, and energy production. It covers topics such as thermodynamics, the metabolic map, ATP's role as an energy carrier, and key metabolic reactions including glycolysis, the TCA cycle, fatty acid oxidation, and amino acid catabolism. Each lecture provides insights into the biochemical processes and their significance in physiotherapy, helping students grasp the biochemical basis necessary for a deeper understanding of human physiology and health.

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Understanding Catabolic Pathways in Physiotherapy

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  1. Catabolic Pathways2nd Year Physiotherapy By Eman Mokbel Alissa, Ph.D.

  2. Lecture (1) Contents • Metabolism Introduction • Thermodynamics • Catabolism and Anabolism • Metabolic Map • Examples of metabolic pathways

  3. Lecture (2) Contents • Bioenergetics Definition • Biomedical Importance • Central Reactions of Metabolism • ATP as energy carrier • ATP, ADP, and AMP structures • ATP / ADP Cycle • Types of Chemical Bonds • Mechanism of Energy Collection • Energy currency

  4. Lecture (3) Contents • Electron Transfer Chain (ETC) • Chemiosmotic Hypothesis • Conservation of ΔG from NADH oxidation in a pH gradient • Respiratory Control

  5. Lecture (4) Contents • Some Points About Glucose • Glucose Oxidation • Fate of Glucose • Glycolysis ATP and NADH production • Alternative Pathways of Pyruvate • TCA Cycle • Summary of ATP Produced

  6. Lecture (5) Contents • Fat and Fatty Acids • Fatty Acid Oxidation • β oxidation • ATP Generation from -Oxidation • β-oxidation in peroxisome • Unsaturated FA oxidation • FA oxidation with odd Carbon No. • α-oxidation

  7. Lecture (6) Contents • Amino acids introduction • N2 Metabolism • Overall flow of nitrogen in amino acid catabolism • Removal of Nitrogen • Combined actions of amintoransferase and glutamate dehydrogenase reactions • Ammonia transport to liver • Urea Cycle • Link between urea cycle and TCA cycle

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