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MAPK Signaling

TNFR. ECM. Hormones. Hormones. RTK. Growth Factor Receptors. Rac1. Rac1. GTP. GTP. GTP. GTP. MEK5. MEK 4/7. MEKK 2/3. MEK 3/6. JNK 1/2/3. JNK 1/2/3. ERK 1/2. ERK 1/2. MLK2/3. MLK3. ERK5. TAK1. Src. IRAK. FAK. TAO1,2. Raf1. A-Raf. MNK. PKA. p38. p38. RIP. PKC.

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MAPK Signaling

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  1. TNFR ECM Hormones Hormones RTK GrowthFactorReceptors Rac1 Rac1 GTP GTP GTP GTP MEK5 MEK4/7 MEKK2/3 MEK3/6 JNK1/2/3 JNK1/2/3 ERK1/2 ERK1/2 MLK2/3 MLK3 ERK5 TAK1 Src IRAK FAK TAO1,2 Raf1 A-Raf MNK PKA p38 p38 RIP PKC PKC KSR ASK ASK MSK MSK PAK c-Raf B-Raf TPL-2 RSK MEKK4 MEKK4 MEKK3 MEKK3 MEKK1 MEKK1 MEKK1 MEKK2 PKA PI3K GPCR Cytokines p130CAS TNF IL-1 OSM 2009 ProteinLounge.com TCF/MEF2 MAPKAPK2 Vinculin Paxillin Paxillin POSH JIP1/2/3 Talin CDC42 TRAF6 TRAF2 GRB2 TRADD SOS Rap1 GPCR c-Myc HSF1 c-Fos STATs p53 CREB CREB TCF Elk1 CHOP ATF c-Jun NF-kB NF-kB GrowthFactors GrowthFactors WNK AC AC PLC PLC MP1 BCL2 Ras N Integrin a b b a N IL-1R C SHC SHC C Gα Gb Gg Gα DAG cAMP MAPK Signaling cAMP DAG MAP3Ks MAPKs MEK1/2 Cell MotilityInflammationApoptosisOsmoregulation Cell ProliferationCell SurvivalTumorigenesisDifferentiationDevelopment Gene Expression CellSurvival C ApoptosisInflammationTumorigenesis GeneExpression

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