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Explore the essential role of water and major minerals in maintaining body fluid balance, nutrient transport, and overall health. Learn about sources, functions, deficiencies, and toxicity levels of key minerals like sodium, potassium, calcium, phosphorus, and magnesium.
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Water • Intracellular Fluid • 2/3 of the body’s water • Extracellular Fluid • Interstitial and Intravascular • Body fluid also contains • Solutes • E.g., Electrolytes: Cations and Anions
Maintenance of Intracellular and Extracellular Fluid Balance • Transmembrane pumps • Sodium, Potassium moved against concentration gradient • Osmosis
Functions of Water • Maintenance of blood volume • Transport of nutrients and oxygen • Fluid synthesis • Lubricant in knees and joints • Solvent in metabolic processes • Temperature Regulation • Specific Heat • Waste Product Removal • urea
Water Sources & Needs • Water in Foods • Sweetened beverages provide little satiety and few micronutrients • Needs • Vary with body size, physical activity, environmental conditions and dietary intake • AI: 15 cups adult men, 11 cups adult women • Based on 80% fluid intake, 20% food intake • Needs met when intake = output
Overview of Minerals • Major versus Trace Minerals • Food Sources • Functions • Deficiencies • Calcium, potassium, magnesium , iron, zinc, and iodine • Toxicity
Sodium (Na+) • Foods • Grains, processed foods, soups and sauces • Needs • AI: 1,500mg (under age 51) • DV: 2,400mg
Sodium (Na+) • Functions • Absorption of glucose and some amino acids • Normal muscle and nerve function • Water balance • Deficiency • Rare (hyponatremia) • Excessive perspiration, diarrhea, vomiting • Excess and Upper Level • UL: 2,300mg
Potassium (K+) • Foods • Unprocessed foods: fruits, vegetables, milk, whole grains • Needs • AI: 4,700mg • DV: 3,500mg • Typical US adult intake falls below both
Potassium (K+) • Functions • Major cation inside cells • High intake suppresses renin-angiotensis system and promotes excretion of sodium • Deficiency • Hypokalemia (life-threatening) • Depletion by some diuretics • Excess and Upper Level • Hyperkalemia (also life-threatening) • In poor kidney function • No UL set
Chloride (Cl-) • Foods • Salt (NaCl) • Needs • AI: 2,300mg • Functions • Main anion in extracellular fluid • Nerve impulse transmission, HCl, immune response, acid-base balance • Deficiency • UL: 3,600mg
Calcium (Ca++) • Foods • Dairy, fortified foods, green leafy vegetables • Bioavailability issues • Needs • RDA: 1,000mg to 1,200mg, 1,300mg in adolescents • DV: 1,000mg • U.S. intake is 720mg to 1,195mg (lower in women) • Calcium supplements • Blood calcium levels regulated tightly
Functions of Calcium (Ca++) • Bone development and maintenance • Cortical and trabecular bone • Bone remodeling • Osteoblasts, osteocytes and osteoclasts • Blood clotting • Transmission of nerve impulses to target cells • Tetany • Muscle contraction • Cell metabolism • Calmodulin system
Calcium (Ca++) • Potential health benefits of calcium • Colon cancer prevention • Protects against formation of oxalate kidney stones • Blood pressure effect • Upper Level • 2500mg • Hypercalcemia can lead to kidney stones
Osteoporosis • Bone Loss • Normal/low bone mass: osteopenia • Very low bone mass: osteoporosis • Kyphosis (Dowager’s hump) • Diagnosis • DEXA bone scan • Prevention • Bone building nutrients • Active lifestyle with weight-bearing activities • Not smoking • Drug therapy
Phosphorus • Foods • Milk, cheese, meat, bakery products, and cereals • Needs • RDA: 700mg • DV: 1,000mg • Average intake is 950 mg to 1650 mg/day
Phosphorus • Functions • Major component of bone and teeth • Critical to the function of every body cell • Part of ATP • Role in hypertension prevention • Deficiency • Rare but a chronic deficiency contributes to bone loss, decreased growth and poor tooth development • Toxicity and Upper Level • UL: 3-4 grams/day
Magnesium (Mg++) • Foods • Part of chlorophyll – plant products • Smaller amounts from hard water, milk, and meats • Needs • RDA: 400mg men, 310mg women (19-30) • Increases 10-20mg over age 30 • DV: 400mg • Fewer than 25% of US adults meet RDA
Magnesium (Mg++) • Functions • Vital role in range of biochemical and physiological processes • Deficiency • Irregular heartbeat, weakness, muscle spasms • Increases risk of osteoporosis • Upper Level • 350mg from supplements and nonfood items only