Grants 101: An Introduction to NIH Grants. Lynn Clemow, Ph.D. Overview. Outline the organization of the National Institutes of Health Program Announcements and RFAs Describe commonly-used grant mechanisms Application and Review Process. Structure of the NIH. Intramural Research
Lynn Clemow, Ph.D.
Grants & Contracts
AIDS Research - Disease Prevention
Behavioral & Social Science Research (OBSSR)
Each person and item needs to be justified in budget justification section of grant
Many K-award mechanisms:
For early-career researchers, this kind of award is the “Holy Grail”.
Some K grants are more basic-science focused
Some with more clinical scientist focus:
There are many others…Important to note that each I/C uses these mechanisms differently – important to check
SMALLER/ DEVELOPMENTAL GRANTS: Used in different ways by different I/Cs
May request up to 2 years of funding @$50,000 / year. Great for pilot data for larger study.
May request up to 2 years for project, with TOTAL of $275,000. Often used to develop and pilot test an intervention.
SMALLER / DEVELOPMENTAL GRANTS
To support a discrete, specific project
Need to have pilot & feasibility data and a team with necessary expertise (preferably some of whom have worked together before)
Large program-projects or center grants
Led by senior investigators (supported by collaborative interdisciplinary group)
Usually made up of 3-4 interacting projects and several shared core functions (biostatistics/ data management, administration, training, instrumentation, laboratories, etc.)
Budgets usually $1.5 million/year for 5 years, goes up for competitive renewal every 5 years
Whole bunch of RFAs, used differently by I/Cs.
Page limits apply to these sections
Also need to include:
Have to get internal sign-offs
Financial disclosure from each investigator
Grants office, financial review of budgets.
Admin. sign-off from departments, facilities
Submissions done electronically in almost all cases at this time… to grants.gov via grants office
1 = perfect score; 9 = worst possible score
Score Descriptor Additional Guidance on Strengths/Weaknesses
Minor Weakness: An easily addressable weakness that does not substantially lessen impact
Moderate Weakness: A weakness that lessens impact
Major Weakness: A weakness that severely limits impact
The final overall impact/priority score: Average of OVERALL IMPACT/PRIORITY SCORES OF REVIEW PANEL MEMBERS to one decimal point and multiplying by ten. Thus, the new scores range from 10-90 in whole numbers.
Payline: 15% - grant is nearly sure to be funded
Can’t be absolutely sure until the Council meets (3 times/year) and confirms payline.
Later: Notice of Grant Award is issued (that’s the actual money)