'Cell receptor' presentation slideshows

Virus Attachment, Entry and Uncoating

Virus Attachment, Entry and Uncoating. Virus Properties. Virus is defined as a nucleoprotein complex which infects cells and uses their metabolic processes to replicate Smallest known infective agents

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Chapter 14 B Lymphocytes

Chapter 14 B Lymphocytes. Contents. B cell receptor and B cell complex B cell accessory molecules B cell subpopulations Functions of B cells B cell maturation BCR diversity and TCR diversity. I. B cell antigen receptor and B cell receptor complex. BCR BCR complex

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Immunology 2 nd Med 2009

Immunology 2 nd Med 2009. Some revision points Con Feighery. Lecture content. How to recognise T cells and B cells Structure of the T cell receptor The different types of T cells The role of MHC in activation of T cells How cytokines influence the immune system. Monocytes / macrophages.

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Prevention Of Type 1 Diabetes Mellitus: Current Status And Future Directions

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A T-cell precursors migrate from the bone marrow to thymus

A T-cell precursors migrate from the bone marrow to thymus. Shaping the T-cell repertoire. Positive and negative selection Thymus. Few TCR reacts with the MHC (about 2%) most T-cells d i e of neglect. ( no survival signals). ? -chain rearrangement can continue until the assembly of

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B CELL DEVELOPMENT IN THE BONE MARROW

B CELL DEVELOPMENT IN THE BONE MARROW. a. a. O RDERED B -CELL DEVELOPMENT. immature B cell. pre B cell. ANTIGEN RECOGNIZING RECEPTOR H 2 L 2. pro B cell. H-chain + surrogate L-chain SIGNALING RECEPTOR. NO ANTIGEN RECOGNIZING RECEPTOR. B. B. Stromal cell.

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Immunol mol med 2

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Reticular fibers

Reticular fibers. Overview. Cytotoxic T cells. B Cells. Antigen Presenting Cells. Helper T cells. Activate. Help Activate. Help Activate. Cell mediateted immunity. antibody mediateted immunity.

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Clonal Diversification of Lymphocytes

Clonal Diversification of Lymphocytes. Review of last lecture. Whereas Mature T cells proliferate when they contact antigens. Whenever immature pre-T Cells recognize self-antigens, they are programmed to auto-destruct in the Thymus. Thymus. Bone Marrow .

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Aims

Aims. Gene rearrangement and class switching of B-cell Igs. T cell receptors- What are they and where do they fit into immunology? Gene rearrangement to generate diversity Readings: Abbas & Lichtman, Chapters 4 & 7. Human Immunoglobulin Loci. Heavy Chain. Light Chain.

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Immunology molecular medicine 3

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How T cells recognize antigen: The T Cell Receptor (TCR)

How T cells recognize antigen: The T Cell Receptor (TCR). Lecture 11, MCB 150 Laurent Coscoy . Identifying the TCR: Why was it so hard to do?. By the early 1980s, much about T cell function was known, but the receptor genes had not been identified

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Immunology/ Pharmacy Students Lymphopoiesis, T and B cells maturation Lecture 3

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Where do T cells come from?

Where do T cells come from?. medulla. cortex. cortex. medulla. cortico-medullary junction. T cell development. Hematopoeitic Stem cell. Lymphoid progenitor. Lymphoblast. Prolymphocyte. Small lymphocyte. T lymphocyte. Lymphoblast. Lymphocyte. Development of the thymus.

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Mapping cancer specific drug-gene interactions

Mapping cancer specific drug-gene interactions. EMBL. Wolfgang Huber Computational Biology. Thorsten Zenz Lymphoproliferative disease DKFZ, Univ. Clinic Heidelberg. Genomics of drug sensitivity: drug screens in pan-cancer cell line panels.

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Virus : A biological particle composed of nucleic acid and protein

Virus : A biological particle composed of nucleic acid and protein pathogen: anything that causes sickness or disease. Viruses. RNA. DNA RNA. Head/Capsid. RNA. Capsid. Capsid proteins. Tail sheath. Tail fiber. Surface proteins. Membrane envelope. Figure 19-9 Virus Structures.

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GTX-001: A Risk Worth Taking

GTX-001: A Risk Worth Taking. 2009 YBPS Case Competition November 20, 2009. Victoria Clark, Kelly Fitzgerald Minji Kim, Frederick Wang Juliana Mastronunzio. Licensing Proposal from Gastrex. Two drug candidates for inflammatory bowel disease: GTX-001 and GTX-002.

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The Antitumor Immune Response

The Antitumor Immune Response. Structures of Class I and Class II Major Histocompatability Complex (MHC) Molecules. With permission from Abbas et al. Cellular and Molecular Immunology . 1994. Pathway of Antigen Presentation by Antigen-Presenting Cells.

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Scientist Profile

Scientist Profile . Index. Biography Project Success References . Biography. Name : Tak Wah Mak

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Structure of hepatitis E virus-like particle suggests mechanisms Sol M. Gruner, Cornell University, DMR 0225180.

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