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Explore the intricate process of DNA replication, where each strand holds the key to duplicating the genetic code. Understand the significance of complementary base pairing and the vital role of DNA polymerase in this fundamental biological mechanism.
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DNA Replication
HOW IS DNA COPIED? structure The __________ of DNA explains how it can be copied. Each strand has all the info needed to construct the __________other half. If strands are separated, _____________ rules allow you to fill in the complementary bases. matching base-pairing
What is the Complementary Strand? G T A C T T G C C A
What is the Complementary Strand? G T A C T T G C C A C A T G A A C G G T
DNA Replication • DNA copies itself exactly, every time the cell divides • This process is called replication
Replication: • Why? • When cells replicate, each new cell needs its own copy of DNA. • Where? • Nucleus in Eukaryotes. • Cytoplasm in Prokaryotes • When? • S phase of interphase in the cell cycle • How?
Steps in Replication • 2 strands unwind • New nucleotides are added to complement the template (original) strands • Strands separate and rewind into 2 molecules (each with 1 old and 1 new strand)
Sites where strand separation and replication occur are called _____________ replication forks Original strand DNA polymerase New strand Growth DNA polymerase Growth Replication fork Replication fork Nitrogenous bases New strand Original strand
DNA Replication 1 old + 1 new strand = semiconservative replication
DNA Replication • Can replicate in 3 minutes (happens at many points at the same time) • Cell proofreads and repairs most mistakes (mutations)