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We will have 5 groups. Groups must have at least 4 and no more than 5

We will have 5 groups. Groups must have at least 4 and no more than 5 Students will be numbered off if the groups cannot be formed quickly You will review the Jeopardy for 20 minutes This is time for review – not finishing homework

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We will have 5 groups. Groups must have at least 4 and no more than 5

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  1. We will have 5 groups. Groups must have at least 4 and no more than 5 • Students will be numbered off if the groups cannot be formed quickly • You will review the Jeopardy for 20 minutes • This is time for review – not finishing homework • There will be a group game the last 20 minutes of class – winning team will receive +2 bonus • Each group member will sign-up on a sheet that is going around • This will be used for the game.

  2. Each group will get a question of equal point value • When it is your group’s turn, I will roll the dice. The number that it rolls will determine which group member answers the question (based on the number you signed up for) • Your team will get 1 “ask the group” (30 seconds) • If a team misses a question, the next team has an opportunity to answer the question (you must have an answer ready) – if you miss, you lose the points

  3. JEOPARDY THE LYMPHATIC SYSTEM

  4. Intro 100 This gland promotes the development of T-cells. What are the 3 organs of MALT? Check Answer

  5. INTRO 100 Thymus Tonsils, Peyer’s Patches, Appendix Go Back to Game Board

  6. INTRO 200 This duct drains lymphatic fluid (from all areas except the upper right quadrant) This vein connects the lymphatic system back to the circulatory system Check Answer

  7. INTRO 200 Thoracic Subclavian Go Back to Game Board

  8. INTRO 300 These lymphatic vessels originate in the small intestines and are involved in the absorption of fats Check Answer

  9. INTRO 300 Lacteals Go Back to Game Board

  10. INTRO 400 These are 4 differences between lymphatic vessels and veins Check Answer

  11. INTRO 400 Thinner walls More valves Encounter lymph nodes along the way Lymph circulates with less pressure Lymph doesn’t contain erythrocytes Go Back to Game Board

  12. INTRO 500 These are the vessels entering lymph nodes These are the vessels exiting lymph nodes Which is more numerous? What are 3 functions of the spleen? CHECK ANSWER

  13. INTRO 500 These are the vessels entering lymph nodes = Afferent These are the vessels exiting lymph nodes = Efferent Which is more numerous? = Afferent Recycles red blood cells; Hemopoesis; Blood resevoire GO BACK TO GAME BOARD

  14. Disease 100 Term for a disease causing agent This is a disease that causes B-cells to swell and look like monocytes (causes symptoms of fatigue and malaise) Check Answer

  15. Disease 100 Pathogen Mononucleosis Go Back to Game Board

  16. Disease 200 Explain why you need booster shots every few years. How does HIV eventually lead to death? Check Answer

  17. Disease… 200 Memory cells die over time HIV weakens immune system and makes one susceptible to opportunistic infections Go Back to Game Board

  18. Disease 300 Indicate the Immunity indicated: 1) Passed from mother to newborn 2) Previously had the disease 3) Received a vaccine 4) Received Antibodies Check Answer

  19. DISEASES… 300 • Indicate the Immunity indicated: • 1) Passed from mother to newborn = NATURALLY, ACQUIRED PASSIVE • 2) Previously had the disease = NATURALLY, ACQUIRED ACTIVE • 3) Received a vaccine = ARTIFICIALLY, ACQUIRED ACTIVE • 4) Received Antibodies = ARTIFICIALLY, ACQUIRED PASSIVE Go Back to Game Board

  20. DISEASES 400 WHAT WOULD HAPPEN IF LYMPH NODES WERE REMOVED IN A CERTAIN AREA? What nodes are removed in breast cancer? Check Answer

  21. DISEASES… 400 • THE AREA WOULD ACCUMULATE LYMPH FLUID AND SWELL • Axillary Go Back to Game Board

  22. DISEASES… 500: INDICATE THE AREA THAT CORRESPONDS TO THE FOLLOWING LYMPH NODES1) INGUINAL2) AXILLARY3) SUPERFICIAL CUBITAL4) SUPERFICIAL CERVICAL5) SUBMAXILLARIndicate the part affected by the following autoimmune diseases:a) Rheumatoid arthritis b) Juvenile diabetes c) Alopecia d) Albinism e) Multiple Sclerosis Check Answer

  23. PHYSIOLOGY 500 LYMPH NODES1) INGUINAL= GROIN 2) AXILLARY = ARMPIT 3) SUPERFICIAL CUBITAL = ELBOW 4) SUPERFICIAL CERVICAL = NECK 5) SUBMAXILLAR = FLOOR OF MOUTH Indicate the part affected by the following autoimmune diseases:a) Rheumatoid arthritis = Joints b) Juvenile diabetes = insulin producing beta cells c) Alopecia = hair follicles d) Albinism = melanocytes e) Multiple sclerosis = myelin sheath Go Back to Game Board

  24. 1st and 2nd… 100 A primary example of the 1st line of defense is: Check Answer

  25. 1st and 2nd… 200 List 4 examples of the 2nd line of defense Check Answer

  26. 1st and 2nd… 300 Migration of phagocytes to a region is called: Destruction of pathogens by drilling small holes in them is called: : Check Answer

  27. 1st and 2nd… 400 THESE CAUSE CELLS TO PRODUCE PROTEINS TO INTERFERE WITH VIRAL REPLICATION THESE non-specific defense CELLS CAUSE CYTOLYSIS OF PATHOGENS THESE PHAGOCYTES ARE THE FIRST TO ARRIVE THESE PHAGOCYTES ARE THE LARGEST AND MOST EFFICIENT Check Answer

  28. 1ST AND 2ND… 500 What is the advantage of vasodilation and a fever? THESE PROTEINS BIND TO IRON SO THAT BACTERIA CANNOT THESE PROTEINS CAUSE CYTOLYSIS, CHEMOTAXIS, AND OPSONIZATION Check Answer

  29. 1ST AND 2ND.. 100 INTACT SKIN Go Back to Game Board

  30. 1ST AND 2ND 200 FEVER INFLAMMATION PHAGOCYTES N.K. CELLS INTERFERRON TRANSFERRIN COMPLIMENT Go Back to Game Board

  31. 1ST AND 2ND 300 CHEMOTAXIS CYTOLYSIS Go Back to Game Board

  32. 1ST AND 2ND 400 • THESE CAUSE CELLS TO PRODUCE PROTEINS TO INTERFERE WITH VIRAL REPLICATION = INTERFERRON • THESE CELLS CAUSE CYTOLYSIS OF PATHOGENS = NATURAL KILLER CELLS • THESE PHAGOCYTES ARE THE FIRST TO ARRIVE AND IN LARGEST NUMBER = NEUTROPHILS • THESE PHAGOCYTES ARE THE LARGEST AND MOST EFFICIENT = MACROPHAGES Go Back to Game Board

  33. 1ST AND 2ND 500 FEVER = INCREASES ENZYME SPEED, SLOWS DOWN BACT. REPRODUCTION VASODILATION = ALLOWS QUICKER MIGRATION OF W.B.C.s TO AREA TRANSFERRIN COMPLIMENT Go Back to Game Board

  34. 3RD… 100 THESE CELLS ARE RESPONSIBLE FOR CELL MEDIATED IMMUNITY: THESE ARE RESPONSIBLE FOR ANTI-BODY MEDIATED IMMUNITY Check Answer

  35. 3RD LINE - 200 THESE STIMULATE THE DEVELOPMENT OF B-CELLS INTO ANTIBODY-PRODUCING PLASMA CELLS Check Answer

  36. 3RD LINE… 300 THESE CELLS REMAIN ALIVE FOR YEARS AND REMEMBER THE INITIAL INFECTION THESE T-CELLS ARE THE “SOLDIERS” THAT DESTROY THE PATHOGENS THESE CELLS WILL PRODUCE ANTIBODIES Check Answer

  37. 3RD LINE… 400 What 2 things must happen to activate T-cells? Check Answer

  38. ANTIBODY (HUMORAL) MEDIATED CELL MEDIATED 1)___-CELLS 8) ___-CELLS 2) BOND TO ________ (FROM APC) APC OR BOND DIRECTLY TO ANTIGEN 3) COSTIMULATION 4) 9) 10) __________ CELLS 12)___________ B CELLS 5)________T-CELLS 6)_____________(KILLER) T-CELLS 7)___________ T-CELLS 11)___________ (IgGS) ) 13) 3RD LINE…500 • What cell type initially bonds to the antigen from the antigen presenting cell and then activates cytotoxic t-cells and B-cells? • EXPLAIN WHY YOU DO NOT GET SICK UPON YOUR 2ND EXPOSURE TO A PREVIOUSLY ENCOUNTERED PATHOGEN Check Answer

  39. 3RD LINE 100 T-CELLS B-CELLS Go Back to Game Board

  40. 3RD LINE 200 HELPER T-CELLS Go Back to Game Board

  41. 3RD LINE 300 • MEMORY CELLS • CYTOTOXIC (KILLER) T-CELLS • PLASMA CELLS Go Back to Game Board

  42. 3rd Line… for 400 • THE ANTIGEN MUST BE PRESENTED BY THE A.P.C. (SUCH AS A MACROPHAGE) and costimulation must occur Go Back to Game Board

  43. 3rd Line… 500 – Helper T-cellsMemory cells quickly clone into Killer T and Plasma cells to destroy pathogen Go Back to Game Board

  44. MISC. for 100 A disease in which the body attacks itself is called: Check Answer

  45. MISC. for 200 List 4 auto-immune diseases. Check Answer

  46. MISC for 300 - Is HIV considered an autoimmune disease? Why or why not? Check Answer

  47. MISC for 400 This organ is an important blood reservoir. These lymphocytes give rise to antibody producing cells. The proteins on a cell that identifies it and promotes an immune response is called a/an: Check Answer

  48. 500 Misc Place the steps of infection in order • Macrophages present antigen to a matching Helper T-cell causing it to activate • Helper T-cells clone and differentiate into Helper and Memory T-cells. They activate matching Cytotoxic T-cells • B-cells bond to antigen and are costimulated by Helper T-cells • B-cells clone and differentiate into plasma cells and memory b-cells • Neutrophils arrive • Macrophages arrive • Pathogen gets past the 1st line of defense • Infected cells release compliment proteins, histamine, and fever causing agents. Vasodilation and chemotaxis occurs • Suppressor T-cells diminish the immune response once the pathogen is destroyed • Plasma cells make antibodies which help to destroy the pathogen Check Answer

  49. MISC for 100 Autoimmune Go Back to Game Board

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