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Immune System Day 4: Understanding Non-specific Defenses

Learn about non-specific immunity, phagocytic cells, natural killer cells, and more to strengthen your body's defenses. Finish the day with a quiz to test your knowledge!

rajah-merrill
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Immune System Day 4: Understanding Non-specific Defenses

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  1. Immune System Day 4 "Treasure the love you receive above all. It will survive long after your good health has vanished."-Og Mandino

  2. Today’s Agenda • Finish Non-specific immunity notes • Quiz • Specific immunity notes—obj. 9, 10

  3. Bacterial leprosy infection just under skin.

  4. “border line leprosy—numb centers

  5. 2. Phagocytic cells--macrophages • Phagocytes include macrophages and neutrophils • Phagocytes engulf and destroy pathogens • Phagocytosis is enhanced when pathogens surface is altered by antibodies or complement proteins • Cell killing is enhanced by respiratory burst

  6. Obj. 6 • 3. Natural killer cells – attack and lyse body cells infected by viruses or that are cancerous.

  7. Obj. 7 Inflammatory response • 1. Skin & mucous membranes • 2. Phagocytic cells • 3. Natural killer cells • 4. Inflammatory response • damaged tissues release histamines • Histamines make vessels leaky, releasing phagocytes & clotting factors • Phagocytes engulf bacteria • Platelets form clots

  8. Obj. 7

  9. Obj. 5 Nonspecific Defenses: things your body uses to defend against ANYTHING • 5. Antimicrobial substances • Interferon • Complement proteins

  10. Obj. 8 Fever • 1. Skin & mucous membranes • 2. Phagocytic cells • 3. Natural killer cells • 4. Inflammatory response • 5. Antimicrobial substances • 6. Fever • Macrophages release pyrogens • Hypothalamus elevates temperature • Liver & spleen supply less iron • Bacteria don’t grow well without iron • Metabolism increases speeding repair. 105 98.6

  11. Ready for a Quiz???

  12. Objective 9 • B & T cells come from bone marrow. • B’s mature in bursa (bone) • T’s mature in thymus

  13. Objective 10 • Antigens are substances capable of causing an immune response.

  14. variable region

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