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Adhesive-Free Mechanical Interface System Design for Microfluidic Chip

This project aims to design and test a mechanical port interface system (MPIS) for microfluidic chips without using adhesives. The MPIS employs flush nut and ferrule interconnects to link capillary tubing with chip ports, enhancing material durability. Acrylic material was chosen for its durability and manufacturability, ensuring leak-proof performance at 30 psi pressure over 3 days. The modified MPIS system aligns with the Agilent Capillary Electrophoresis instrument, enabling efficient exploration of novel microfluidic chips using capillary electrophoresis techniques.

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Adhesive-Free Mechanical Interface System Design for Microfluidic Chip

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  1. Mechanical Interface System Design for Microfluidic Chip C. Wheeler, J. Kwan, J. Maung, T. LuMechanical Engineering, 2005-2006Sponsors and Advisors: Dr. J. Lee, Dr. M. Goedert, Dr. R. Yee ABSTRACT The objective of our project is to design, prototype, and test an adhesive free mechanical port interface system (MPIS) for a microfluidic chip. Instead of using adhesives, the MPIS utilizes a flush nut and ferrule interconnects to interface capillary tubing with the ports of the microfluidic chip. Due to high material durability and good manufacturability, acrylic was selected as the material to fabricate the MPIS. The interface was experimentally verified to be leak-proof over 3 days at 30 psi pressure. BROADER IMPACT The MPIS system was modified to fit with the Agilent Capillary Electrophoresis instrument, which will help researchers explore the effectiveness of novel microfluidic chips using capillary electrophoresis. (1) the MPIS, (2) a microfluidic chip, (3) a microfluidic chip utilizing adhesive fittings for capillary to port interconnection, and (4) an Agilent Capillary Electrophoresis instrument.(Note: you can also put important equations or graphics instead of pictures in the above space).

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