DYSLIPIDEMIAS: TYPES I-V. Thomas F. Whayne, Jr, MD, PhD, FACC Professor of Medicine (Cardiology) University of Kentucky March 2011. E-Mail: firstname.lastname@example.org . No conflicts to declare. THE MAJOR LIPOPROTEINS. CHYLOMICRONS. VERY LOW DENS. LIPOPROT. (VLDL).
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Thomas F. Whayne, Jr, MD, PhD, FACC
Professor of Medicine (Cardiology)
University of Kentucky
No conflicts to declare.
Tube with KB
STORMY JONES: AGE 10.
ACCELERATED ATHEROSCLEROSIS: CORONARY AND PERIPHERAL
APO E IN LIVER RECEPTORS IS ABNORMAL OR DEFICIENT FOR:
or CV DYSMETABOLIC SYNDROME
AT LEAST 3 OF THE FOLLOWING 5 PRESENT†:
TG 150 mg/dl.
HDL < 40 mg/dl in men and < 50 mg/dl in women .
BP 130/85 mm/Hg.
Waist girth > 102 cm (men) and > 88 cm (women).
Fasting glucose 100 mg/dl.
dense LDL, Insulin resistance, Hyperuricemia, PAI-1, hsCRP, Tissue necrosis factor-α Interleukin-6, Resistin, and Adiponectin.
†Grundy SM, et al. Circulation 2005;112:2735-2752.
47 million or 23% of US adults have the metabolic syndrome
Adapted from: Ford ES, et al. JAMA2002;287:356-359.
SPORADICALLY AND UNPREDICTABLY, ESTROGEN MAY CAUSE A MARKED ELEVATION IN TRIGLYCERIDES.
MULTIPLE APPROACHES AVAILABLE TO ACHIEVE GOOD BLOOD LIPID CONTROL AND THEREBY AVOID MULTIPLE CLINICAL PROBLEMS INCLUDING SEQUELAE OF CORONARY ATHEROSCLEROSIS.