Destruction of Organophosphorus Nerve Agent Analogues by Activation of O2 under Aqueous Room Temperature and Atmospheric

1. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 1 Destruction of Organophosphorus Nerve Agent Analogues by Activation of O2 under Aqueous Room Temperature and Atmospheric Pressure Conditions Christina Noradoun, Ryan Hutcheson, Edmund Wong, I. Francis Cheng* University of Idaho, Department of Chemistry, Moscow, ID 83844-2343 ifcheng@uidaho.edu; 208-885-6387

2. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 2 Overall Goal

3. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 3 Oxidative Pathways

4. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 4 Reactive Oxygen Forms

5. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 5 Partially Reduced Oxygen

6. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 6 That Last Step: The Fenton Reaction

7. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 7 The Proposed System

8. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 8 Putting the System Together �The Reducing Agent

9. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 9 Putting the System Together � Oxygen Activation Agents

10. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 10 Putting the System Together � Fenton�s Reagent

11. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 11 Summary of Van Eldik Study

12. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 12 Our System

13. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 13 Method for Detection of Facile Oxidant from O2 Actiavtion

14. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 14 TBARS Results

15. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 15 Summary of the New System

16. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 16 Xenobiotic Oxidation Studies

17. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 17 Xenobiotic Oxidation Studies

18. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 18 Oxidation of Chlorophenols

19. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 19 Reaction Vessel

20. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 20 4-CP Degradation Kinetic Studies

21. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 21 Summary of the degradation of the chlorophenols in this study

22. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 22 Organophosphorous Agents

23. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 23 Control Studies

24. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 24 Summary of Identified Intermediates

25. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 25 Kinetics of Malathion Degradation

26. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 26 Malaoxon

27. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 27 Unidentified Intermediate

28. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 28 Ion Chromatography of other Ionic Products and Intermediates

29. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 29 Summary of Intermediates

30. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 30 Kinetically stable organic species in the presence of aqueous Fe(0)/EDTA/O2.

31. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 31 pH Control and Possible Role

32. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 32 Technical Summary

33. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 33 Scientific Summary

34. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 34 Future Investigations

35. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 35 Desorption Studies

36. January 29, 2012 Frank Cheng, ifcheng@uidaho.edu 36