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van Leeuwenhoek (17 th century) de Graaf (17 th century) Early 19 th century – blending theory

Chapter 14 Mendel and the Gene Idea [ Mendelian genetics: The scientific study of heredity and hereditary variation]. van Leeuwenhoek (17 th century) de Graaf (17 th century) Early 19 th century – blending theory. ?. X.

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van Leeuwenhoek (17 th century) de Graaf (17 th century) Early 19 th century – blending theory

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  1. Chapter 14Mendel and the Gene Idea[Mendelian genetics: The scientific study of heredity and hereditary variation] van Leeuwenhoek (17th century) de Graaf (17th century) Early 19th century – blending theory

  2. ? X

  3. 14.2Crossing pea plants (“genetic crosses”) – Gregor Mendel(19th century) Discrete heritable factors

  4. 14.3Mendel tracked heritable characters for three generations Both purple and white=flowered plants appear in the F2 generation in a ratio of approximately 3:1

  5. Sweet pea flowers

  6. 14.4 Alleles, alternative versions of a gene

  7. Table 14.1 Results of Mendel’s F1 Crosses for Seven Characters in Pea Plants

  8. 14.5 Mendel’s law of segregation (Layer 1)

  9. 14.5 Mendel’s law of segregation (Layer 2)

  10. 14.6 Genotype versus phenotype

  11. Round and wrinkled peas SS or Ss ss

  12. 14.7A testcross

  13. 14.8Testing two hypotheses for segregation in a dihybrid cross. Do alleles sort independently? Recombinant phenotypes

  14. 14.9 Segregation of alleles and fertilization as chance events

  15. 1) Black fur in mice (B) is dominant to brown fur (b). Short tails (T) is dominant to long tails (t). What proportion of the progeny of the cross BbTt multiply BBtt will have black fur and long tails? A) 6/16 B) 8/16 C) 9/16 D) 3/16 E) 1/16 2) Tallness (T) is dominant to dwarfness (t), while red (R) flower color is dominant to white (r). The heterozygous condition results in pink (Rr) flower color. A dwarf red snapdragon is crossed with a plant homozygous for tallness and white flowers. What are the genotype and phenotype of the F1 individuals? A) TtRr - tall and pink B) ttRr - dwarf and pink C) TtRr - tall and red D) TTRR - tall and red E) ttrr - dwarf and white

  16. 14.10 Incomplete dominance in snapdragon color Carnation

  17. Pleiotropic effects of the sickle-cell allele in a homozygote Single gene  multiple effects

  18. 14.14 The effect of environment of phenotype Norm of reaction for a genotype: The range of phenotypic possibilities due to environmental influence Alkaline Acid

  19. 14.13.A simplified model for polygenic inheritance of skin color.(Mating between individuals who are heterozygous for all three genes) Multiple genes  single effect Three separately-inherited genes affect the darkness of skin

  20. 14.11.Multiple alleles for the ABO blood groups.Blood types are the result from various combinations of three different alleles (IA, IB and i)

  21. 14.15 Pedigree analysis

  22. 14.15 Pedigree analysis

  23. Large families provide excellent case studies of human genetics Albinism Cystic fibrosis Huntington’s disease

  24. 14.19Testing a fetus for genetic disorders

  25. Concept 14.1. Two laws of inheritance (Mendel) Concept 14.2. Applying the law of probability to Mendelian genetics. Concept 14.3. Inheritance patterns are often more complex than predicted by Mendelian genetics. Concept 14.4. Many human traits follow Mendelian patterns Also look at tips for solving genetic problems (p. 283). See Chapter 14 Review (p. 282-283)

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