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Gas Exchange. By Adriana Jimenez & Daisy Martinez. Ventilation, or breathing, is the alternate inspiration (inhaling) and expiration (exhalation) of air. Terrestrial vertebrates rely on ventilation to maintain high O2 and low CO2 concentrations at the gas exchange surface.

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Gas exchange

Gas Exchange

By Adriana





42 6 breathing ventilates the lungs

42.6 : Breathing Ventilates the Lungs


How an amphibian breathes

How an Amphibian Breathes

How a mammal breathes
How a Mammal Breathes: (inhaling) and expiration (exhalation) of air.

  • Lungs pull air into the lungs with the use of muscle action: rib muscles and diaphragm contract.

    • lung volume increases.

  • Negative Pressure Breathing.

How mammals breathe
How mammals breathe… (inhaling) and expiration (exhalation) of air.

  • Visceral Pump: in some species, running causes the visceral organs (like the stomach & liver) to slide back and forth in the body cavity with each stride, this further increases ventilation volume.

  • Tidal volume: the volume of air a mammal inhales and exhales with each breath.

  • Vital capacity: the maximum tidal volume.

  • Residual Volume: the air that remains in the lungs.

Control of breathing in humans
Control of Breathing in Humans: (inhaling) and expiration (exhalation) of air.

  • Breathing control centers: located in medulla oblongata and the pons; the medulla sets the basic rhythm, while the pons moderates it.

  • Sensors in carotid arteries in the neck and in the walls of the aorta help monitor O2 and CO2 concentrations and blood pH.

  • Low O2 concentration leads to an increased breathing rate to offset the CO2 levels

  • Low pH leads to an increased breathing rate, can lead to hyperventilation

42 7 respiratory pigments bind transport genes

  • The role of partial Pressure gradients (inhaling) and expiration (exhalation) of air.

  • Respiratory pigments

    • Respiratory pigments transport gases and help buffer the blood. Respiratory pigments greatly increase the amount of 02 that blood can carry.

42.7: Respiratory Pigments Bind & Transport Genes


The role of partial pressure gradients

The Role ofPartial Pressure Gradients

Loading and unloading of respiratory gases
Loading and unloading of respiratory gases in air or dissolved in water, depends on differences in a quantity.

1. blood arriving at the lungs via the pulmonary arteries has a lower Po2 and a higher P co2 than the air in the alveoli.

2. by the time the blood leaves the lungs in the pulmonary veins, its Po2 has been raised and its Pco2 has been lowered.

After returning to the heart, this blood is pumped through the systematic circuit.

3. in the tissue capillaries, gradients of partial pressure favor the diffusion of o2 out of the blood and co2 into the blood.

Because cellular respiration removes o2 from and adds co2, to the interstitial fluid. (by diffusion, from mitochondria in nearby cells.)

4. after the blood unloads o2 and loads co2 it is returned to the heart and pumped to the lungs again.

Where it exchanges gases with air in the alveoli.

Respiratory pigments

Respiratory Pigments

Oxygen transport

A diversity of respiratory pigments have evolved in various animal taxa.

  • Hemoglobin, Respiratory Pigment of almost all vertebrates.

    • Consists of 4 subunits, called a heme group that has an iron atom at its center.

    • Each molecule can carry 4 molecules of O2. Also helps transport CO2 and assists in buffering.

OXYGEN transport

Oxygen transport1

Oxygen Transport

Oxygen transport cont

  • Loading and unloading depends on cooperation between the subunits of the hemoglobin molecule.

  • A slight change in O2 Partial Pressures causes hemoglobin to load or unload O2 .

  • When cells in a particular location begin working harder(during exercise) PO2 dips in their vicinity as O2 is consumed in cellular respiration.

Oxygen transport cont…

Dissociation curve
Dissociation curve subunits of the hemoglobin molecule.

  • Bohr Shift: a drop in pH lowers the affinity of hemoglobin for O2.

  • When carbonic acid forms, an active tissue lowers the pH of its surrounds and induces hemoglobin to release more O2.

(b) pH&Hemoglobin Dissociation

Co 2 transport
CO subunits of the hemoglobin molecule.2 Transport

BIBLIOGRAPHY subunits of the hemoglobin molecule.

  • Campbell, Neil A., and Jane B. Reece. "Chapter 42.6-7." Biology. 7th ed. San Francisco: Pearson, Benjamin Cummings, 2005. 888-90. Print.

  • Egan, Donald F., Robert L. Wilkins, James K. Stoller, and Robert M. Kacmarek. "Carbon Dioxide and Cerebral Blood Flow." Egan's Fundamentals of Respiratory Care. 9th ed. St. Louis, MO: Mosby/Elsevier, 2009. 313-14. Print.

  • Marieb, Elaine Nicpon, Jon Mallatt, Patricia Brady. Wilhelm, and Matt Hutchinson. "Chapter 21 - The Respiratory System." Human Anatomy. 5th ed. San Francisco, CA: Pearson, 2010. 614+. Print

  • Benjamin Cunning, . "Chapter 42 - Circulation and Gas Exchange." Pearson Education, 2005. Web. 11 Mar 2012.