A daptive I mmune S ystem. Angela Mitchell BIO422 2013 email@example.com. “Jobs” of the Immune System. “Jobs” of the Immune System. Recognize that invaders are present Recognize that these are different than self Recruit more cells/factors to fight invaders Kill the invaders
T cell Mediated Immunity
What do cytotoxic T cells recognize?
T helper 1 cells (Th1) are important for defense from…
Epitopes and Antigens
MHCI and MHCII
Activation of T cells
Croft. 2003. Nat Rev Immun. 3: 609.
B cell Mediated Immunity
Secondary responses to infection
Jenner (around 1796)
to cowpox did not get smallpox
(vaccinia) and the boy did not
get sick with smallpox
The roles of IgE and mast cells
Nature Reviews Immunology 2001 (1) 69-75