Prothrombin time and coagulation time. Coagulation Cascade. Intrinsic pathway Extrinsic pathway Common pathway The extrinsic pathway was required the addition of an exogenous trigger (originally provided by tissue extracts).
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The extrinsic pathway was required the addition of an exogenous trigger (originally provided by tissue extracts).
the intrinsic pathway required only exposing factor XII (Hageman factor)
to a thrombogenic surface (even glass would suffice).
Intrinsic system (surface contact)
Extrinsic system (tissue damage)
Vitamin K dependant factors
A number of common artefactual causes which should be considered if a long time is not expected. These include the following: