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Origins of Life: From Ancient Philosophies to Modern Scientific Discoveries

Explore the fascinating journey of life's origins, tracing theories from ancient thinkers like Lao-Tzu to pivotal experiments by Francesco Redi and Louis Pasteur that debunked spontaneous generation. Delve into the concepts of abiogenesis and heterogenesis, and discover the insights of Darwin and A.I. Oparin on primordial soup theory. Understand the significance of Stanley Miller's 1953 experiments and the implications of the Oxygen Revolution, highlighting the endosymbiont hypothesis and advancements in sexual reproduction.

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Origins of Life: From Ancient Philosophies to Modern Scientific Discoveries

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  1. Where Does Life Come From?

  2. Origins of Life (pre-19th c.) • Abiogenesis • Heterogenesis

  3. Lao-Tzu

  4. Francisco Redi (1668)

  5. LazzaroSpallanzani (1768)

  6. Louis Pasteur (1864)

  7. “Never again will the doctrine of spontaneous generation recover from the mortal blow struck by this simple experiment”

  8. Darwin

  9. A.I. Oparin (& David Haldane)

  10. Primordial Soup 4.4 bya Oceans have pH of 5.8 Present: CH4, NH3, H2O, H2S, CO2, CO Absent: O2 or O3 Highly reducing atmosphere leads to synthesis of amino acids

  11. Stanley Miller (& Harold Urey) 1953

  12. Sidney Fox Origin of Coacervates (protocells)

  13. Oxygen Revolution 2.2 bya Caused not only metabolic transition but mass extinction

  14. Endosymbiont Hypothesis (Margulis 1981)

  15. Sexual Reproduction

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