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Enhancing DNA Fork Stability with ChlR1 and FANCJ Proteins: A Biochemical Study

Investigate the impact of ChlR1 and FANCJ proteins on duplex ssDNA fork stability. Experimental results reveal the unwound percentage under varying protein concentrations. Findings contribute to understanding DNA replication mechanisms.

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Enhancing DNA Fork Stability with ChlR1 and FANCJ Proteins: A Biochemical Study

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  1. * 5’ 41 19 3’ Fig. S2 A hChlR1-WT (nM) 0 0.02 0.04 0.08 0.15 0.3 0.6 1.2 2.4 Forked duplex ssDNA FANCJ-WT (nM) 0 0.08 0.15 0.3 0.6 1.2 2.4 * 5’ 26 19 3’ * 5’ 5’ 26 * 41 19 19 B Unwound (%) Protein (nM)

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