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Topic: Blood Typing

Topic: Blood Typing. What is the ABO system?. Genetics of Blood Typing. Multiple alleles- one gene with more than 2 allele forms AA or Ai = type A BB or Bi = type B AB= type AB (codominance) ii = type 0. What happens if you mix the wrong blood types?.

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Topic: Blood Typing

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  1. Topic: Blood Typing What is the ABO system?

  2. Genetics of Blood Typing • Multiple alleles- one gene with more than 2 allele forms • AA or Ai = type A • BB or Bi = type B • AB= type AB (codominance) • ii = type 0

  3. What happens if you mix the wrong blood types? • The antibodies made will stick to the red blood cells and cause clumping. • The clumping is called agglutination.

  4. The Rh Factor • Humans may have a second antigen present on red blood cells. • Most likely caused by dominant gene • If you have it , you are Rh (+) • If you don’t have it, you are Rh (-)

  5. Rh disease • Happens when mom is Rh- and dad is Rh+ • If baby is Rh+, mom will produce Rh antibodies. • First baby may be OK, but second???? • Treatment: Drug called Rhogam.

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