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Drugs. Influences on Drug Use. Biological – heredity Identical twins Adoption studies Boys at age 6 excitable, fearless, impulsive (genetic traits) are more likely to take drugs NPY – brain chemical more sensitive to alcohol Gene identified to predispose people to alcohol dependence

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influences on drug use
Influences on Drug Use
  • Biological – heredity
    • Identical twins
    • Adoption studies
    • Boys at age 6 excitable, fearless, impulsive (genetic traits) are more likely to take drugs
    • NPY – brain chemical more sensitive to alcohol
    • Gene identified to predispose people to alcohol dependence
  • Psychological
    • Lacking sense of purpose
    • Stress
    • Depression
  • Social-cultural
    • Urban enviro
    • Cultural attitude toward drugs
    • Peer influences
drugs1
Drugs
  • Our brain is protected by a layer of capillaries called the blood-brain barrier.
  • The drugs that are small enough to pass through are called psychoactive drugs.
psychoactive drugs
Psychoactive Drugs
  • Psychoactive Drugs - Chemicals that alter moods and perceptions through actions on neural synapses
    • Altered state (altered moods and perceptions)associated with changes in brain activity
  • Examples: alcohol, marijuana, cocaine (depressants, hallucinogens, stimulants)
dependence and addiction
Dependence and Addiction
  • Addiction – compulsive craving for a drug despite adverse consequences
    • What about each of our three major types of drugs make someone want to keep taking them?
      • Sense of well-being, feeling of euphoria , blissful pleasure, relief from anxiety, increased self-confidence, alertness
      • Withdrawal symptoms can contribute to addiction
  • Tolerance – need to take larger and larger doses to experience the same effects
    • Neuroadaptation - change in brain chemistry that offsets the effects of a psychoactive drug
  • Withdrawal – discomfort and distress that follow the discontinued use of certain drugs (aches, nausea, distress)
  • Physical dependence – physiological need for a drug indicated by withdrawal symptoms
  • Psychological dependence – psychological need to use a drug
drugs are either
Drugs are either….
  • Agonists – mimics neurotransmitters
    • Opiates (heroine, morphine) mimic endorphins
  • Antagonists – block neurotransmitters
    • LSD – blocks serotonin
  • Reuptake inhibitors
    • Cocaine – blocks reuptake of dopamine, Ecstasy blocks reuptake of serotonin
depressants
Depressants
  • Slows down body processes and calms neural activity.
    • Breathing slows, pupils constrict, anxiety replaced by pleasure
  • Alcohol
  • Barbiturates/ tranquilizers
  • Opiates (morphine, heroine)
alcohol
Alcohol
  • More than 86 billion dollars are spent annually on alcoholic beverages.
  • Alcohol is involved in 60% of ALL crimes.
  • Alcohol is involved in over 70% of sexually related crimes.
  • Is it worth the cost?
opiates
Opiates
  • Agonist for endorphins.
  • Morphine, heroin, methadone and codeine.
  • Pupils constrict, breathing slows, lethargy, blissful pleasure replaces pain and anxiety
  • Highly addictive
  • Brain stops producing own opiates (endorphins)
    • brain will lack painkilling neurotransmitters after withdrawal
stimulants
Stimulants
  • Excite neural activity and speed up body processes.
    • Increased heart and breathing rates, pupils dilate, appetite diminishes, energy increases
  • More powerful ones (like cocaine) give people feelings of invincibility.
  • Amphetamines
  • Methamphetamines
  • Caffeine
  • Nicotine
  • Cocaine
  • Ecstasy
hallucinogens
Hallucinogens
  • Psychedelics
  • Causes changes in perceptions of reality
  • LSD, peyote, psilocybin mushrooms and marijuana.
  • Reverse tolerance or synergistic effect
slide14

An altered state of consciousness in which people experience fantastic images and often feel separated from their bodies is most closely associated with the use of

  • Heroin
  • Cocaine
  • Barbiturates
  • Marijuana
  • LSD
barbiturates are considered
Barbiturates are considered
  • Stimulants
  • Hallucinogens
  • Depressants
  • Opiates
  • Both a depressant and hallucinogen
what do methamphetamine caffeine and cocaine have in common
What do methamphetamine, caffeine and cocaine have in common?
  • They slow body functions and calm neural activity
  • They depress neural functioning and reduce pain
  • The distort perceptions and evoke sensations without sensory input
  • They excite neural activity and arouse body function
  • They relax the body, lead to disinhibition and produce euphoria