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Transport of CO 2. Dissolved in plasma As bicarbonate ions As carbamino Hb or Carbamino Proteins Under normal resting conditions,an average of 4 ml of CO 2 is transported from tissues to lungs in each 100 ml of blood. Transport of CO2 in Dissolved state.
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Transport of CO2 • Dissolved in plasma • As bicarbonate ions • As carbamino Hb or Carbamino Proteins Under normal resting conditions,an average of 4 ml of CO2 is transported from tissues to lungs in each 100 ml of blood
Transport of CO2 in Dissolved state Accounts for 7% of all the CO2 normally transported • At PCO2 of venous blood 2.7 ml/dl • At PCO2 of arterial blood 2.4 ml/dl i.e. 0.3 ml of CO2 is transported in the form of dissolved CO2 by each dl of blood
Transport as bicarbonate ions { C.A - RBC + - - Accounts for 70% of CO2 transport from cells/ Tissues to lungs. CO2 + H2O H2 CO3 H+ + HCO3 H +Hgb HHgb Cl Cl Plasma
Transport as carbamino Hb Accounts for 23% of CO2 transport from cells to lungs CO2 + Hgb HgbCO2 Or CO2 +Plasma Proteins P.PCO2
Haldane Effect Binding of oxygen of with hemoglobin tends to displace carbon dioxide from the blood or removing oxygen from hemoglobin increases the ability of Hb to pick up carbon dioxide and CO2- generated H .
