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Informatics Lessons from Using a Novel Immunization Information System. David K. Vawdrey, Karthik Natarajan , Andrew S. Kanter , George Hripcsak , Gilad J. Kuperman , Melissa S. Stockwell. NewYork -Presbyterian Hospital (NYP).

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informatics lessons from using a novel immunization information system

Informatics Lessons from Using a Novel Immunization Information System

David K. Vawdrey, KarthikNatarajan,

Andrew S. Kanter, George Hripcsak,

GiladJ. Kuperman, Melissa S. Stockwell

newyork presbyterian hospital nyp
NewYork-Presbyterian Hospital (NYP)
  • NYP is composed of six main facilities located in and around New York City
    • Columbia University Medical Center
    • Weill Cornell Medical Center
    • 2,600 patient beds; 118,000 discharges yearly
immunization challenges
Immunization Challenges
  • Nearly one in five U.S. toddlers do not receivethe prescribed basic immunization series
  • Children are more likely to be under-immunized if they are members of a racial or ethnicminority, are poor, or live in inner-city or rural areas
  • Thousands of children are over-immunized because records of previous vaccinations are not available

National, state, and local area vaccination coverage among children aged 19-35 months--United States, 2006. MMWR Morb Mortal Wkly Rep. Sep 15 2007;56(34):880-885

Feikema SM, Klevens RM, Washington ML, Barker L. Extraimmunization among US children. JAMA. 2000;283(10):1311-1317

fragmentation of immunization records
Fragmentation of Immunization Records
  • About 25% of U.S. children see more than one immunization provider in their first three years of life, leading to fragmented and incomplete vaccination records

Feikema SM, Klevens RM, Washington ML, Barker L. Extraimmunization among US children. JAMA. 2000;283(10):1311-1317

Yusuf H, Adams M, Rodewald L, et al. Fragmentation of immunization history among providers and parents of children in selected underserved areas. Am J Prev Med. Aug 2002;23(2):106-112

newyork presbyterian hospital nyp immunization information system ezvac
NewYork-Presbyterian Hospital (NYP) Immunization Information System (EzVac)
  • Includes all children and adults receiving care at hospital and affiliated ambulatory clinics
    • In use since 1999
    • Over 2 million vaccines for more than 260,000 individuals
  • Functions
    • Aggregates data from multiple EHRs
    • Providescomprehensive immunization records
    • Allows documentation of historical vaccines
    • Prepares schools, daycareand other immunization forms
    • Public health reporting
    • Consumer access
nyp immunization management
NYP Immunization Management
  • Slide here with architecture of EzVac etc plan
exchanging information informatics challenges
Exchanging Information:Informatics Challenges
  • Patient matching
  • Duplicate information
    • Class-level (not vaccine-level) de-duplication process
    • Considered to be “duplicate” if two identical vaccines were given within 10 days
  • Adequacy of standards
    • CVX, MVX, HL7
  • Provenance
    • E.g., patient-recorded data from PHR?
can informatics tools help improve the management of immunization information
Can Informatics Tools Help Improve the Management of Immunization Information?

Percent of children 24-35 months up-to-date on immunizations

Percent of children seen in NYP Ambulatory Care Network clinics who were up-to-date on 4:3:1:3:3:1immunizations compared to national, state and local data from the National Immunization Survey (NIS) Jan-Dec 2011.

text messaging immunization reminders
Text Messaging Immunization Reminders

…a higher proportion of children and adolescents in the intervention group (43.6%; n=1653) compared with the usual care group (39.9%; n=1509) had received influenza vaccine (difference, 3.7% [95% CI, 1.5%-5.9%])

success factors in immunization information sharing
Success Factors in Immunization Information Sharing
  • Forward-thinking leadership from institution and from NYC health department
  • Clinical, informatics and IT expertise for creating a local infrastructure to support information exchange
    • Limitations of vendor EHRs (import data—automated or manual reconciliation, provenance)
    • Terminology standards are inadequate (CVX codes don’t represent vaccine classes)
future directions in immunization information management
Future Directions in Immunization Information Management
  • U.S.
    • “Meaningful Use” Stage 3 proposes bi-directional information exchange with local systems
    • Local systems seldom communicate with one another
  • Decade of Vaccines
    • Shared vision endorsed by 200 nations
    • Extend the benefits of vaccines to every person by 2020 and thereby save more than 20 million lives
  • WHO Global Vaccine Safety Initiative
    • Hundreds of millions of vaccinations are administered each year in developing countries
    • Few vaccination programs “have the ability to monitor and assure the safe use of vaccines.”


Funding support:

  • AHRQ
  • HRSA
  • CDC
  • Microsoft

Recent Publications:

  • Exploring pregnant women’s views on influenza vaccination and educational text messages. Prev Med. 2011 Jan;52(1):75-7
  • FluAlert: A Qualitative Evaluation of Providers' Desired Characteristics and Concerns Regarding Computerized Influenza Vaccination Alert. Prev Med. 2011 Mar-Apr;52(3-4):274-7.
  • Text Message Reminders to Promote Human Papillomavirus Vaccination. Vaccine.2011 Mar 21;29(14):2537-41
  • Timeliness of 2009 H1N1 Vaccine Coverage In A Low-Income Pediatric and Adolescent Population. Vaccine. 2013 Apr 12;31(16):2103-7.
  • Text4Health: Text4Health: Impact of Text Message Reminder-Recalls for Pediatric and Adolescent Immunizations. Am J Public Health. 2012 Feb;102(2):e15-21.
  • Effect of a text messaging intervention on influenza vaccination in an urban, low-income pediatric and adolescent population: a randomized controlled trial. JAMA. 2012 Apr 25;307(16):1702-8.
informatics lessons from using a novel immunization information system1

Informatics Lessons from Using a Novel Immunization Information System